MAK110
MTP Activity Assay Kit
Supplied by Roar Biomedical, Inc.
Sinonimo/i:
MTTP Activity Assay Kit, Microsomal triglyceride transfer protein activity assay kit
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About This Item
Codice UNSPSC:
12161503
NACRES:
NA.84
Prodotti consigliati
impiego
sufficient for 100 fluorometric tests
applicazioni
pharmaceutical
Metodo di rivelazione
fluorometric
Malattie correlate
cardiovascular diseases
Temperatura di conservazione
2-8°C
Informazioni sul gene
human ... MTTP(4547)
Descrizione generale
Microsomal triglyceride transfer protein (MTP), a membrane-bound protein present in the liver, plays an important role in the assembly and secretion of very low density lipoprotein (VLDL). MTP is also necessary for assembly and secretion of chylomicrons by the intestine. This protein facilitates the transfer of triglyceride (TG), cholesteryl ester (CE) and phosphatidylcholine (PC) between phospholipid surfaces. Mutation in the MTP gene leads to abetalipoproteinemia.
Applicazioni
MTP Activity Assay Kit has been used to measure the activity of microsomal triglyceride transfer protein (MTP).
Caratteristiche e vantaggi
Compatible with high-throughput handling systems.
Compatibilità
Suitable for measuring microsomal [triglyceride] transfer protein (MTP) activity in cell lysates or tissue homogenates, or for screening MTP activity inhibitors.
Principio
The MTP Activity Assay Kit is a sensitive, homogeneous fluorometric assay useful for continuous measurement of MTP activity in cell lysate or tissue homogenate. This kit includes proprietary substrates that enable the detection of MTP-mediated transfer of neutral lipid. The transfer activity results in an increase in fluorescence intensity (λEx=465 nm/λEm=535 nm).
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Codice della classe di stoccaggio
10 - Combustible liquids
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