M8877
α-Methyl-DL-m-tyrosine
Sinonimo/i:
α-MMT, DL-2-Methyl-3-(3-hydroxyphenyl)alanine, AMMT
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About This Item
Prodotti consigliati
Temperatura di conservazione
−20°C
Stringa SMILE
CC(N)(Cc1cccc(O)c1)C(O)=O
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European journal of pharmacology, 120(1), 63-68 (1986-01-14)
A comparative study of the ability to block the amine pump was carried out on tricyclic antidepressants including dothiepin and northiaden in vivo. Dothiepin was found to prevent the 6-OHDA-induced depletion of cardiac noradrenaline but not the PCA-induced depletion of
Neuroendocrinology, 38(1), 62-67 (1984-01-01)
To address the issue of whether, after morphine treatment, the reduced release of dopamine (DA) into portal blood is entirely responsible for the increased prolactin (PRL) release, the following study was conducted. The concentration of DA in plasma from a
Journal of cardiovascular pharmacology, 7 Suppl 5, S81-S85 (1985-01-01)
In the adrenergic neurons the amino acid alpha-methyl-meta-tyrosine (alpha-MmT) is converted to metaraminol via the noradrenaline (NA) synthetic pathway. Metaraminol thereby displaces NA from its neuronal stores, and as a consequence NA levels can be drastically reduced, although normal sympathetic
The Journal of pharmacology and experimental therapeutics, 311(2), 576-584 (2004-07-16)
5-Hydroxytryptamine (serotonin) (5-HT) and norepinephrine (NE) are implicated in modulating descending inhibitory pain pathways in the central nervous system. Duloxetine is a selective and potent dual 5-HT and NE reuptake inhibitor (SNRI). The ability of duloxetine to antagonize 5-HT depletion
Pharmacology, 28(3), 130-138 (1984-01-01)
alpha-Methyldopa (alpha-MD) was administered intraperitoneally into adult male mice and its effect on alpha 1- and alpha 2-noradrenergic receptor binding sites in the brain was investigated, using [3H]WB-4101 and [3H]clonidine, respectively. A single injection of 50-200 mg/kg alpha-MD abolished the
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