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L9895

Sigma-Aldrich

Lectin from Pseudomonas aeruginosa

lyophilized powder

Sinonimo/i:

PA-I

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About This Item

Numero MDL:
MFCD00165587
Codice UNSPSC:
12352202
NACRES:
NA.32

Forma fisica

lyophilized powder

Livello qualitativo

200

Potenza

<15 μg/mL per mL agglutination activity

Temperatura di conservazione

−20°C

Azioni biochim/fisiol

PA-I has a major affinity for D-galactose and its derivatives. PA-I agglutinates all types of human and animal erythrocytes and interacts also with unicellular protozoa, algae and bacteria. PA-I induces mitogenic stimulation in cultured human lymphocytes pretreated with neuraminidase.

Confezionamento

Package size based on protein content. Vial content based on protein by biuret.

Qualità

Highly purified.

Stato fisico

Lyophilized powder containing approx. 80% protein (biuret), balance primarily sodium citrate, plus traces of calcium chloride, magnesium chloride and manganese chloride

Nota sulla preparazione

Purified by affinity chromatography using a modification of Gilboa-Garber.1

Risultati analitici

Agglutination activity is expressed in μg/ml and is determined from serial dilutions of a 1 mg/ml solution using phosphate buffered saline, pH 7.0. This activity is the lowest concentration to agglutinate a 2% suspension of neuraminidase treated human blood group A erythrocytes after one hr incubation at 25 °C.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Alessandro Palmioli et al.
Chembiochem : a European journal of chemical biology, 20(23), 2911-2915 (2019-06-20)
Biofilm formation by bacterial pathogens is a hallmark of chronic infections and is associated to increased antibiotic tolerance that makes pathogens difficult to eradicate with conventional antibiotic therapies. Infections caused by Pseudomonas aeruginosa are of great concern, especially for immunocompromised
Akiko Chiba et al.
Molecular cancer research : MCR, 18(1), 130-139 (2019-10-20)
Breast tumors have their own specific microbiota, distinct from normal mammary gland tissue. Patients with breast cancer that present with locally advanced disease often undergo neoadjuvant chemotherapy to reduce tumor size prior to surgery to allow breast conservation or limit

Articoli

Lectin Selection Guide: A Useful Guide for Selecting the Right Lectin

Find the right lectin for your research with our lectin selection guide, organized by lectin source/species, carbohydrate specificity, blood group specificity, and more.

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