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I4161

Sigma-Aldrich

IL-2 mouse

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

Sinonimo/i:

IL-2, Interleukin-2, T-cell growth factor, mIL-2

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20 μG
CHF 332.00

CHF 332.00

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20 μG
CHF 332.00

About This Item

Numero MDL:
MFCD00164816
Codice UNSPSC:
12352202
NACRES:
NA.77

CHF 332.00

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Nome del prodotto

Interleukin-2 from mouse, IL-2, recombinant, expressed in E. coli, carrier free

Origine biologica

mouse

Livello qualitativo

200

Ricombinante

expressed in E. coli

Saggio

≥97% (SDS-PAGE)

Stato

lyophilized powder

Potenza

≤0.2 ng/mL ED50

Qualità

endotoxin tested

PM

17.2 kDa

Confezionamento

pkg of 5X20 μg
pkg of 20 μg

tecniche

cell culture | mammalian: suitable

Impurezze

≤0.200ng/ml

Colore

white

N° accesso UniProt

P04351

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Informazioni sul gene

mouse ... Il2(16183)

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Categorie correlate

Azioni biochim/fisiol

Interleukin-2 (IL-2) is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Stato fisico

Lyophilized with no additives.

Ricostituzione

Centrifuge vial prior to opening. Reconstitute the contents of the vial in water to a concentration range of 0.1-1.0 mg/mL.
IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant human IL-2 is a 15.5 kDa protein, containing 134 amino acid residues including one intrachain disulfide bond.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H319,H335

Classi di pericolo

Eye Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
0000245090
059M4121V
11190317
027M4137V
11121122

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IL-4 from mouse Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

Sigma-Aldrich

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IL-4 from mouse

Concanavalin A from Canavalia ensiformis (Jack bean) Type IV-S, lyophilized powder, aseptically processed, BioReagent, suitable for cell culture

Sigma-Aldrich

C5275

Concanavalin A from Canavalia ensiformis (Jack bean)

Joaquin De Haro et al.
Journal of vascular surgery, 62(6), 1625-1631 (2014-07-22)
This study assessed the effect of cellular and humoral autoimmune response inhibition after immunization with β2-glycoprotein I (β2-GPI) and the effect of immunomodulation with interleukin (IL)-2 and IL-10 in the development of early atherosclerotic vascular lesion in a murine model.
Nabil Ahmed et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 33(15), 1688-1696 (2015-03-25)
The outcome for patients with metastatic or recurrent sarcoma remains poor. Adoptive therapy with tumor-directed T cells is an attractive therapeutic option but has never been evaluated in sarcoma. We conducted a phase I/II clinical study in which patients with
Fang-Ting Lu et al.
Journal of autoimmunity, 61, 62-72 (2015-06-15)
Thymic CD4(+) FoxP3(+) regulatory T (Treg) cells are critical for the development of immunological tolerance and immune homeostasis and requires contributions of both thymic dendritic and epithelial cells. Although B cells have been reported to be present within the thymus
Larisa Kizima et al.
PloS one, 9(4), e94547-e94547 (2014-04-18)
Prevalent infection with human herpes simplex 2 (HSV-2) or human papillomavirus (HPV) is associated with increased human immunodeficiency virus (HIV) acquisition. Microbicides that target HIV as well as these sexually transmitted infections (STIs) may more effectively limit HIV incidence. Previously
X Han et al.
Cell death and differentiation, 21(11), 1758-1768 (2014-07-19)
IL-17 is one of the most potent and most actively investigated proinflammatory cytokines. In this study, we examined the effect of IL-17 on mesenchymal stem cells (MSCs) under the influence of inflammatory cytokines. Ironically, IL-17 dramatically enhanced the immunosuppressive effect
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