H7654
Hydroxyguanidine sulfate salt
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50 MG
CHF 351.00
CHF 351.00
Spedizione prevista il16 aprile 2025
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Cambia visualizzazione
50 MG
CHF 351.00
About This Item
Formula condensata:
CH5N3O · 1/2H2SO4
Numero CAS:
Peso molecolare:
124.11
Numero CE:
Numero MDL:
Codice UNSPSC:
12352202
ID PubChem:
NACRES:
NA.77
CHF 351.00
Spedizione prevista il16 aprile 2025
Prodotti consigliati
Origine biologica
synthetic (organic)
Livello qualitativo
Saggio
≥98% (TLC)
Stato
powder
Solubilità
water: 25 mg/mL, clear, colorless
Temperatura di conservazione
2-8°C
Stringa SMILE
NC(=N)NO.NC(=N)NO.OS(O)(=O)=O
InChI
1S/2CH5N3O.H2O4S/c2*2-1(3)4-5;1-5(2,3)4/h2*5H,(H4,2,3,4);(H2,1,2,3,4)
MTGDDPZRXSDPFH-UHFFFAOYSA-N
Azioni biochim/fisiol
An early antitumor agent. Oxidation results in release of NO, and formation of other reactive oxygen species, including peroxynitrite and peroxyl radicals.[1] Reacts with NO to form an adduct which is a potent and stable vasodilator.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Patrick Slama et al.
Biochemical and biophysical research communications, 316(4), 1081-1087 (2004-03-27)
Conversion of neurotransmitter dopamine into norepinephrine is catalyzed by dopamine beta-hydroxylase (DbH). The reaction requires the presence of both molecular oxygen and a reducing cosubstrate, the assumed physiological cosubstrate being ascorbic acid. We have investigated the ability of a new
Daniel Mansuy et al.
Free radical biology & medicine, 37(8), 1105-1121 (2004-09-29)
Nitric oxide (NO) is a key inter- and intracellular molecule involved in the maintenance of vascular tone, neuronal signaling, and host response to infection. The biosynthesis of NO in mammals involves a two-step oxidation of L-arginine (L-Arg) to citrulline and
Patrick Slama et al.
Journal of inorganic biochemistry, 103(3), 455-462 (2009-01-31)
N-Aryl-N'-hydroxyguanidines are compounds that display interesting pharmacological properties but their chemical reactivity remains poorly investigated. Some of these compounds are substrates for the heme-containing enzymes nitric-oxide synthases (NOS) and act as reducing co-substrates for the copper-containing enzyme Dopamine beta-Hydroxylase (DBH)
Zhi-guo Zhang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 39(9), 705-710 (2004-12-21)
To search for novel antiasthmatic agents. Coupling seratrodast (SD), an antiasthmatic drug, with several different types of NO donors including oxatriazoles, N-hydroxyguanidines and furoxans; evaluating the antiasthmatic effects of coupled compounds by determining their inhibitory activity of guinea pig asthma
David Lefèvre-Groboillot et al.
The FEBS journal, 272(12), 3172-3183 (2005-06-16)
The binding of several alkyl- and aryl-guanidines and N-hydroxyguanidines to the oxygenase domain of inducible NO-synthase (iNOS(oxy)) was studied by UV/Vis difference spectroscopy. In a very general manner, monosubstituted guanidines exhibited affinities for iNOS(oxy) that were very close to those
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