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Documenti fondamentali

E0789

Sigma-Aldrich

Casein, Hammarsten bovine

Sinonimo/i:

Casein from bovine milk

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500 G
CHF 251.00
5 KG
CHF 1’240.00

CHF 251.00


Spedizione prevista il30 maggio 2025



Scegli un formato

Cambia visualizzazione
500 G
CHF 251.00
5 KG
CHF 1’240.00

About This Item

Numero CAS:
Numero CE:
Numero MDL:
Codice UNSPSC:
12352202
NACRES:
NA.61

CHF 251.00


Spedizione prevista il30 maggio 2025


Origine biologica

bovine milk (Hammarsten)

Saggio

>90% dry basis

Stato

powder

tecniche

enzyme immunoassay: suitable

Punto di fusione

280 °C (dec.) (lit.)

N° accesso UniProt

Temperatura di conservazione

room temp

Stringa SMILE

[P](=O)(OCC(NC(=O)C(NC(=O)C(N)Cc1ccccc1)CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(C(O)C)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(C

InChI

1S/C81H125N22O39P/c1-36(2)31-50(76(132)94-43(15-24-57(87)108)71(127)101-52(34-64(120)121)78(134)98-49(81(137)138)11-7-8-30-82)99-72(128)47(19-28-61(114)115)95-77(133)51(33-63(118)119)100-73(129)48(20-29-62(116)117)97-80(136)65(37(3)104)103-75(131)44(16-25-58(88)109)92-68(124)42(14-23-56(86)107)90-67(123)41(13-22-55(85)106)91-69(125)45(17-26-59(110)111)93-70(126)46(18-27-60(112)113)96-79(135)53(35-142-143(139,140)141)102-74(130)40(12-21-54(84)105)89-66(122)39(83)32-38-9-5-4-6-10-38/h4-6,9-10,36-37,39-53,65,104H,7-8,11-35,82-83H2,1-3H3,(H2,84,105)(H2,85,106)(H2,86,107)(H2,87,108)(H2,88,109)(H,89,122)(H,90,123)(H,91,125)(H,92,124)(H,93,126)(H,94,132)(H,95,133)(H,96,135)(H,97,136)(H,98,134)(H,99,128)(H,100,129)(H,101,127)(H,102,130)(H,103,131)(H,110,111)(H,112,113)(H,114,115)(H,116,117)(H,118,119)(H,120,121)(H,137,138)(H2,139,140,141)
BECPQYXYKAMYBN-UHFFFAOYSA-N

Informazioni sul gene

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Descrizione generale

Casein is an amphiphilic protein.[1]
Casein, a phosphoprotein, is the principal protein component of milk which is almost entirely expressed in the lactating mammary gland.[2] In bovine milk they are classified according to their calcium sensitivity: αs1-, αs2-, and β-caseins precipitate in the presence of calcium; whereas κ-casein remains in solution. [3]

Applicazioni

Casein, Hammarsten bovine has been used as a substrate for Aplysia californica calpain to study its activity.[4]
The product is useful as a protease substrate.

Azioni biochim/fisiol

Casein is useful in food industries and non-food applications. It has the property for emulsification, foam formation, and stabilization, water-binding, and gelation. Casein is also considered heat and acid-stable.[1]
Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3


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I clienti hanno visto anche

Margaret H Hastings et al.
PloS one, 12(10), e0186646-e0186646 (2017-10-21)
Calpains are a family of intracellular proteases defined by a conserved protease domain. In the marine mollusk Aplysia californica, calpains are important for the induction of long-term synaptic plasticity and memory, at least in part by cleaving protein kinase Cs
Krisztina Nagy et al.
The Journal of biological chemistry, 285(50), 38811-38817 (2010-10-06)
The possible mechanism of casein aggregation and micelle buildup was studied in a new approach by letting α-casein adsorb from low concentration (0.1 mg·ml(-1)) solutions onto the charged surfaces of polyelectrolyte films. It was found that α-casein could adsorb onto
Andreas F Kolb et al.
PloS one, 6(7), e21775-e21775 (2011-07-27)
The major physiological function of milk is the transport of amino acids, carbohydrates, lipids and minerals to mammalian offspring. Caseins, the major milk proteins, are secreted in the form of a micelle consisting of protein and calcium-phosphate.We have analysed the
Bovine beta-casein: Isolation, properties and functionality. A review
Atamer Z, et al.
International dairy journal, 66, 115-125 (2017)

Questions

  1. 製薬会社で医薬品の品質試験を行なっている者です。このカゼイン(Hammerstein)において、日局等の公定書に基づいて赤外吸収スペクトル測定法の臭化カリウム錠剤法の試験を実施した実績がありますでしょうか。もしなければ、実施実績のある他のカゼイン(Hammerstein)製品の取扱いはございますでしょうか。ご回答お願いいたします。

    1 answer
    1. There are currently two Hammerstein versions of Casein available, E0789 and 1.02242. Neither of these products are tested according to the JP.

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