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Merck

D7409

2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt

≥90% (HPLC)

Sinonimo/i:

ddGTP

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2 MG

CHF 583.10

CHF 583.10

Prezzo di listinoCHF 686.00Risparmia il 15%
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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C10H16N5O12P3
Numero CAS:
Peso molecolare:
491.18
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Assay:
≥90% (HPLC)
Form:
powder
Solubility:
water: 5 mg/mL, clear, colorless
Storage temp.:
−20°C

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Quality Level

assay

≥90% (HPLC)

form

powder

solubility

water: 5 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

[Na+].OP([O-])(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]1CC[C@@H](O1)n2cnc3C(=O)NC(=N)Nc23

InChI

1S/C10H16N5O12P3.Na/c11-10-13-8-7(9(16)14-10)12-4-15(8)6-2-1-5(25-6)3-24-29(20,21)27-30(22,23)26-28(17,18)19;/h4-6H,1-3H2,(H,20,21)(H,22,23)(H2,17,18,19)(H3,11,13,14,16);/q;+1/p-1/t5-,6+;/m0./s1

InChI key

XCOBCPBPAINELA-RIHPBJNCSA-M

Gene Information

human ... HRAS(3265)

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Questo articolo
D9250D9500D4010
Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥90% (HPLC)

assay

≥90% (HPLC)

assay

≥99% (HPLC)

assay

≥96% (HPLC)

form

powder

form

powder

form

powder

form

powder

solubility

water: 5 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear, colorless

solubility

water: 50 mg/mL, clear, colorless

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Gene Information

human ... HRAS(3265)

Gene Information

-

Gene Information

-

Gene Information

-

Application

2′,3′-Dideoxyguanosine 5′-triphosphate (ddGTP) is use as a chain terminator inhibitor and a inhibitor of telomerase(s).

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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C Strahl et al.
Molecular and cellular biology, 16(1), 53-65 (1996-01-01)
The ribonucleoprotein telomerase, a specialized cellular reverse transcriptase, synthesizes one strand of the telomeric DNA of eukaryotes. We analyzed telomere maintenance in two immortalized human cell lines: the B-cell line JY616 and the T-cell line Jurkat E6-1, and determined whether
A Bart et al.
Nucleic acids research, 33(14), e124-e124 (2005-08-11)
The identification of methylated sites on bacterial genomic DNA would be a useful tool to study the major roles of DNA methylation in prokaryotes: distinction of self and nonself DNA, direction of post-replicative mismatch repair, control of DNA replication and
Y Li et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(17), 9491-9496 (1999-08-18)
The Taq DNA polymerase is the most commonly used enzyme in DNA sequencing. However, all versions of Taq polymerase are deficient in two respects: (i) these enzymes incorporate each of the four dideoxynucleoside 5' triphosphates (ddNTPs) at widely different rates
A Y Howe et al.
Hepatology (Baltimore, Md.), 23(1), 87-96 (1996-01-01)
Hepatitis B virus (HBV) replication is mediated by the viral polymerase that possesses three functional domains: primer, DNA polymerase/reverse transcriptase, and RNase H. Using the Pekin duck as an animal model, we demonstrate a novel mechanism of inhibition of duck
Joeri Auwerx et al.
Molecular pharmacology, 61(2), 400-406 (2002-01-26)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are specific for human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and do not inhibit HIV-2. Given that the amino acids lining the NNRTI-specific pocket of HIV-1 RT display higher similarity to the corresponding

Numero articolo commerciale globale

SKUGTIN
D7409-2MG04061833588529

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