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D131

3,5-Dinitrocatechol

solid

Sinonimo/i:

3,5-Dinitro-1,2-benzenediol, OR-486

Autenticati per visualizzare i prezzi organizzativi e contrattuali.

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Cambia visualizzazione
Taglio della confezioneSKUDisponibilitàPrezzo
50 mg
Per conoscere la disponibilità, visualizza il carrello
CHF 293.00

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C6H4N2O6
Numero CAS:
7659-29-2
Peso molecolare:
200.11
NACRES:
NA.77
PubChem Substance ID:
24278158
UNSPSC Code:
12352202
MDL number:
MFCD00069263

CHF 293.00

Per conoscere la disponibilità, visualizza il carrello
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biological source

synthetic (organic)

Quality Level

200

assay

≥98% (HPLC)

form

solid

color

yellow

mp

168-170  °C

solubility

H2O: slightly soluble 0.17 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.8 mg/mL, 0.1 M HCl: slightly soluble, DMSO: soluble, aqueous buffer pH > 5: soluble, ethanol: soluble

storage temp.

2-8°C

SMILES string

Oc1cc(cc(c1O)[N+]([O-])=O)[N+]([O-])=O

InChI

1S/C6H4N2O6/c9-5-2-3(7(11)12)1-4(6(5)10)8(13)14/h1-2,9-10H

InChI key

VDCDWNDTNSWDFJ-UHFFFAOYSA-N

Gene Information

human ... COMT(1312)

Application

3,5-Dinitrocatechol (3,5-DNC) has been used in the preparation of the molybdenum (VI)-(3,5-DNC) complex.[1][2] It has also been used as a catechol-O-methyltransferase (COMT) inhibitor and as a positive control for screening human COMT inhibition.[3]
Chelating reagent used in a sensitive (μM) assay for vanadium.

Biochem/physiol Actions

Selective inhibitor of catechol O-methyl transferase (COMT); penetrates the blood brain barrier and is useful both orally and parenteraly in experiments where inhibition of COMT in the central nervous system is required.

Analysis Note

Solutions may be stored for several days at 4 °C.

Disclaimer

Photosensitive

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Questo articolo
R108N7510D9641
3,5-Dinitrocatechol solid

Sigma-Aldrich

D131

3,5-Dinitrocatechol

Ro 41-0960 solid

Sigma-Aldrich

R108

Ro 41-0960

Nicardipine hydrochloride powder, ≥98%

Sigma-Aldrich

N7510

Nicardipine hydrochloride

Deoxygalactonojirimycin hydrochloride

Sigma-Aldrich

D9641

Deoxygalactonojirimycin hydrochloride

biological source

synthetic (organic)

biological source

-

biological source

-

biological source

synthetic (organic)

assay

≥98% (HPLC)

assay

-

assay

≥98%

assay

≥98% (HPLC)

Gene Information

human ... COMT(1312)

Gene Information

human ... COMT(1312)

Gene Information

human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

Gene Information

-

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

form

solid

form

solid

form

powder

form

powder or solid

solubility

H2O: slightly soluble 0.17 mg/mL, 0.1 M HCl: slightly soluble, aqueous buffer pH > 5: soluble, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.8 mg/mL, ethanol: soluble, DMSO: soluble

solubility

H2O: slightly soluble <0.7 mg/mL, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.0 mg/mL, ethanol: soluble

solubility

DMSO: ~1 mg/mL, 0.1 M NaOH: insoluble, H2O: slightly soluble, methanol: soluble

solubility

water: soluble 1 mg/mL

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
0000287895
0000287895
SLCP5279
SLCF6118
SLBT2326

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V W Couling et al.
Biophysical journal, 75(2), 1097-1106 (1998-07-24)
This paper presents a study of the use of ultraviolet resonance Raman (UVRR) spectroscopic methods as a means of elucidating aspects of drug-protein interactions. Some of the RR vibrational bands of the aromatic amino acids tyrosine and tryptophan are sensitive
A K Pani et al.
General pharmacology, 31(1), 67-73 (1998-05-22)
1. The efficacies of various agents that affect monoamine synthesis, oxidation and methylation were evaluated in the scallop, Placopecten magellanicus, through the use of high performance liquid chromatography with electrochemical detection. 2. Central ganglia, labial palps and feet from animals
Kirila Stojnova et al.
Acta chimica Slovenica, 65(1), 213-220 (2018-03-22)
The equilibria of the chelate formation and ion-association in the liquid-liquid extraction system Mo(VI)‒3,5-DNC‒INT‒H2O‒CHCl3 were studied by spectrophotometry. The optimum conditions for the chelate formation and extraction of the ion-associated complex formed between the anionic chelate of Mo(VI)‒3,5-dinitrocatechol (3,5-DNC) and
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Numero articolo commerciale globale

SKUGTIN
797391-200MG04061832939643
D131-50MG04061832947129
D131-250MG04061832947112

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