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Merck
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C9504

Sigma-Aldrich

Coenzyme Q6

Sinonimo/i:

2,3-Dimethoxy-5-methyl-6-(farnesylfarnesyl)-1,4-benzoquinone, Ubiquinone-30

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About This Item

Formula empirica (notazione di Hill):
C39H58O4
Numero CAS:
1065-31-2
Peso molecolare:
590.88
Numero MDL:
MFCD00055698
Codice UNSPSC:
12352204
ID PubChem:
24893163

Origine biologica

Saccharomyces cerevisiae

Temperatura di conservazione

−20°C

Stringa SMILE

COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C)=C(C)C1=O

Confezionamento

Sealed ampule.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves

Certificati d'analisi (COA)

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Sergio Padilla-López et al.
Biochimica et biophysica acta, 1788(6), 1238-1248 (2009-04-07)
Coenzyme Q is an isoprenylated benzoquinone lipid that functions in respiratory electron transport and as a lipid antioxidant. Dietary supplementation with Q is increasingly used as a therapeutic for treatment of mitochondrial and neurodegenerative diseases, yet little is known regarding
Alejandro Martín-Montalvo et al.
The Biochemical journal, 440(1), 107-114 (2011-08-05)
CoQ(6) (coenzyme Q(6)) biosynthesis in yeast is a well-regulated process that requires the final conversion of the late intermediate DMQ(6) (demethoxy-CoQ(6)) into CoQ(6) in order to support respiratory metabolism in yeast. The gene CAT5/COQ7 encodes the Cat5/Coq7 protein that catalyses
C J Sippel et al.
The Journal of biological chemistry, 258(2), 1057-1061 (1983-01-25)
Increasing concentrations of glucose (1-5%) in the growth medium depressed ubiquinone-6 biosynthesis in continuously cultured wild type Saccharomyces cerevisiae. In addition, an early intermediate in the pathway of ubiquinone-6 biosynthesis, i.e. 3,4-dihydroxy-5-hexaprenylbenzoate (3,4-DHHB), was found to accumulate. The increase in
Peter Gin et al.
The Journal of biological chemistry, 278(28), 25308-25316 (2003-05-02)
Coenzyme Q (Q) is a lipid that functions as an electron carrier in the mitochondrial respiratory chain in eukaryotes. There are eight complementation groups of Q-deficient Saccharomyces cerevisiae mutants, designated coq1-coq8. Here we have isolated the COQ6 gene by functional
S Padilla et al.
Cellular and molecular life sciences : CMLS, 66(1), 173-186 (2008-11-13)
Coenzyme Q is a lipid molecule required for respiration and antioxidant protection. Q biosynthesis in Saccharomyces cerevisiae requires nine proteins (Coq1p-Coq9p). We demonstrate in this study that Q levels are modulated during growth by its conversion from demethoxy-Q (DMQ), a
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