C6499
CTB
≥98% (HPLC)
Sinonimo/i:
CTPB, N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide
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Cambia visualizzazione
| A voi/SKU | Disponibilità | Prezzo |
|---|---|---|
5 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 76.10 |
25 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 204.00 |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C16H13ClF3NO2
Numero CAS:
Peso molecolare:
343.73
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Servizio Tecnico
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Permettici di aiutartiQuality Segment
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: >10 mg/mL
storage temp.
2-8°C
SMILES string
FC(F)(F)c1c(ccc(c1)NC(=O)c2c(cccc2)OCC)Cl
InChI key
YDXZSNHARVUYNM-UHFFFAOYSA-N
General description
CTB (N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide) is derived from anacardic acid.
Application
CTB has been used to study its apoptotic effects on P53 protein acetylation.
Biochem/physiol Actions
CBP (CREB binding protein)/p300) histone acetyltransferases (HATs) activator; p300 HAT activator.
CTPB was a first known small molecular activator of histone acetyltransferase p300. CTB is a simplified analog of CTPB with comparable or higher activity. The compound activates the histone acetyltransferase (HAT) activity of p300/EP300/E1A binding protein.
Small molecule activators of HAT such as CTB (N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide) is useful for altering chromatin acetylation directly. It might serve as a therapeutic agent for treating the complications of cognitive dysfunction including neuropsychiatric, neurodevelopmental and neurodegenerative diseases.
Features and Benefits
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
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Questo articolo | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥95% (HPLC) | assay ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility DMSO: >10 mg/mL | solubility DMSO: ≥10 mg/mL | solubility DMSO: 20 mg/mL, clear | solubility DMSO: 10 mg/mL, clear |
| color white to off-white | color white to beige | color white to beige | color white to beige |
Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 2
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