C4024

Carbamazepine

≥98% (HPLC), powder, antiepileptic agent

• Sinonimo/i: 5H-Dibenz[b,f]azepine-5-carboxamide
• Formula empirica (notazione di Hill): C₁₅H₁₂N₂O
• Numero CAS: 298-46-4
• Peso molecolare: 236.27
• Numero CE: 206-062-7
• Numero MDL: MFCD00005073
• Codice UNSPSC: 12352200
• eCl@ss: 34051404
• ID PubChem: 57654002
• NACRES: NA.77

Proprietà

• product name: Carbamazepine, powder
• Forma fisica: powder
• Punto di fusione: 191-192 °C (lit.)
• Solubilità: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 29 mg/mL; H₂O: insoluble; ethanol: soluble; propylene glycol: soluble
• Ideatore: Novartis
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: NC(=O)N1c2ccccc2C=Cc3ccccc13
• InChI: 1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18); FFGPTBGBLSHEPO-UHFFFAOYSA-N
• Informazioni sul gene: human ... BZRAP1(9256) , GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , PRNP(5621) , SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335) ; rat ... Scn2a1(24766) , Scnn1a(25122) , Scnn1g(24768) , Slc6a1(79212)

Descrizione

Applicazioni

Carbamazepine has been used to investigate its behavior in wastewater treatment and during groundwater infiltration. It has also been used to find out its effects on spontaneous seizures in rats.

Azioni biochim/fisiol

Carbamazepine is considered as a safe antiepileptic drug. It decreases the multiple drug therapy and maintains a better control of epilepsy.

Anticonvulsant; ligand for the GABA_A receptor benzodiazepine modulatory site. Sodium channel inhibitor.

Caratteristiche e vantaggi

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• Pittogrammi: GHS08,GHS07
• Avvertenze: Danger
• Indicazioni di pericolo: H302,H317,H334,H336,H360FD
• Consigli di prudenza: P202 - P261 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Classi di pericolo: Acute Tox. 4 Oral - Repr. 1A - Resp. Sens. 1 - Skin Sens. 1A - STOT SE 3
• Organi bersaglio: Central nervous system
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves