B5683

Betaxolol hydrochloride

>98% (HPLC), calcium channel blocker, solid

• Sinonimo/i: SL 75212
• Formula empirica (notazione di Hill): C₁₈H₂₉NO₃ · HCl
• Numero CAS: 63659-19-8
• Peso molecolare: 343.89
• NACRES: NA.77
• PubChem Substance ID: 24278274
• UNSPSC Code: 12352200
• EC Number: 264-384-3
• MDL number: MFCD00242959
• Assay: >98% (HPLC)
• Form: solid
• Storage condition: desiccated

Proprietà

• Nome del prodotto: Betaxolol hydrochloride, >98% (HPLC)
• Quality Segment: 100
• assay: >98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white
• solubility: H₂O: soluble 36 mg/mL
• originator: Alcon
• SMILES string: Cl[H].CC(C)NCC(O)COc1ccc(CCOCC2CC2)cc1
• InChI: 1S/C18H29NO3.ClH/c1-14(2)19-11-17(20)13-22-18-7-5-15(6-8-18)9-10-21-12-16-3-4-16;/h5-8,14,16-17,19-20H,3-4,9-13H2,1-2H3;1H
• InChI key: CHDPSNLJFOQTRK-UHFFFAOYSA-N
• Gene Information: human ... ADRB1(153)

Descrizione

Application

Betaxolol hydrochloride has been used as a β1 blocking agent:

• for the preparation of crystals of (R,S)-betaxolol (BE-IV).
• to treat mammalian cells prior cell stimulation experiments.
• to study the solid structure of metoprolol.

Biochem/physiol Actions

Betaxolol hydrochloride has the ability to block calcium channels. Betaxolol is a selective β1 adrenoreceptor antagonist. It has neuroprotective effects on retinal neurons.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Alcon. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informazioni sulla sicurezza

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves