AV32623

Anti-HIC1 antibody produced in rabbit

affinity isolated antibody

• Sinonimo/i: Anti-Hypermethylated in cancer 1
• Codice UNSPSC: 12352203
• NACRES: NA.43

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous solution
• PM: 74 kDa
• Reattività contro le specie: human
• Concentrazione: 0.5 mg - 1 mg/mL
• tecniche: western blot: suitable
• N° accesso NCBI: NP_001091672
• N° accesso UniProt: Q14526-2
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... HIC1(3090)

Descrizione

Descrizione generale

HIC1 is a tumor suppressor that interacts with SIRT1 to regulate p53-depenedent responses to DNA damage.
Rabbit Anti-HIC1 antibody recognizes human, mouse, and rat HIC1.

Immunogeno

Synthetic peptide directed towards the N terminal region of human HIC1

Applicazioni

Rabbit Anti-HIC1 antibody can be used for western blot applications at a concentration of 0.25μg/ml.

Azioni biochim/fisiol

HIon Channel1 is a transcriptional repressor. HIon Channel1 may act as a tumor suppressor. HIon Channel1 may be involved in development of head, face, limbs and ventral body wall. Defects in HIon Channel1 may be a cause of the facial dysmorphism and additional birth defects (except for lissencephaly) seen in the contiguous gene disorder Miller-Dieker syndrome (MDS), like defective development of the nose, jaws, extremities, gastrointestinal tract, and kidney.

Sequenza

Synthetic peptide located within the following region: ALCASERRCSPLCGLDLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPA

Stato fisico

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable