A4034

(+)- L-ascorbato di sodio

powder, BioReagent, suitable for cell culture

• Sinonimo/i: Acido L(+)-ascorbico, Vitamina C
• Formula empirica (notazione di Hill): C₆H₇NaO₆
• Numero CAS: 134-03-2
• Peso molecolare: 198.11
• Beilstein: 3767246
• Numero CE: 205-126-1
• Numero MDL: MFCD00082340
• Codice UNSPSC: 12352205
• eCl@ss: 34058010
• ID PubChem: 24890738
• NACRES: NA.75

Proprietà

• Origine biologica: synthetic (organic)
• Nome Commerciale: BioReagent
• Saggio: ≥98%
• Forma fisica: powder
• PM: M_w 135.13 g/mol
• tecniche: cell culture | mammalian: suitable; cell culture | plant: suitable
• Colore: white to off-white
• Punto di fusione: 220 °C (dec.) (lit.)
• Solubilità: H₂O: 50 mg/mL
• Stringa SMILE: [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
• InChI: 1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1; PPASLZSBLFJQEF-RXSVEWSESA-M

Descrizione

Descrizione generale

(+)-Sodium L-ascorbate (SA) is a potential antioxidant and is a derivative of vitamin C (L-ascorbic acid). It is widely used as a food additive. In addition, SA enhances growth retardation activity of bleomycin sulfate, R020-1724 (an inhibitor of cyclic nucleotide phosphodiesterase), prostaglandin E1 and sodium butyrate agents on neuroblastoma cells in culture. Elevated levels of SA induces two-stage urinary bladder carcinogenesis in rats. sodium L-ascorbate in combination with collagenogenesis inhibitors is used to treat dermal scars and keloids.

Applicazioni

(+)-Sodium L-ascorbate has been used:

• to produce H₂O₂ in cell culture media
• as a reducing agent for a cell-permeable artificial electron donor, N,N,N′,N′-tetramethyl-p-phenylenediamine (TMPD)
• to study its effect on production of collagen and elastic fibers in fibroblasts cultures derived from normal human skin and dermal fat

Used for preparation of plant extracts; reductant for the isolation of chloroplasts.

Azioni biochim/fisiol

Antioxidant

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)