The purpose of the charcoal purification step is to remove fatty acids from the albumin solution, and it has been verified that no traces of charcoal are present in the final product. As for ensuring that components of the buffer used for lyophilization are not present in the final product, it is currently considered salt-free, but there is potential to characterize it by ICP-MS.
A1887
Albumina
lyophilized powder, essentially fatty acid free
Sinonimo/i:
HSA
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Cambia visualizzazione
| Voi/SKU | Disponibilità | Prezzo |
|---|---|---|
100 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 61.10 |
500 mg | Per conoscere la disponibilità, visualizza il carrello | CHF 119.00 |
1 g | Per conoscere la disponibilità, visualizza il carrello | CHF 281.00 |
5 g | Per conoscere la disponibilità, visualizza il carrello | CHF 910.00 |
10 g | Per conoscere la disponibilità, visualizza il carrello | CHF 1090.00 |
25 g | Per conoscere la disponibilità, visualizza il carrello | CHF 2310.00 |
Informazioni su questo articolo
Numero CAS:
UNSPSC Code:
12352202
eCl@ss:
42010201
EC Number:
274-272-6
NACRES:
NA.25
MDL number:
Biological source:
human
Assay:
≥96% (agarose gel electrophoresis)
Form:
lyophilized powder
Technique(s):
ELISA: suitable, tissue culture: suitable, western blot: suitable
Impurities:
HIV I and HIVII, HCV and HBsAg, tested negative, ≤0.007% Fatty Acids
Servizio Tecnico
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Permettici di aiutartibiological source
human
Quality Segment
assay
≥96% (agarose gel electrophoresis)
form
lyophilized powder
mol wt
monomer calculated mol wt 66478 Da
technique(s)
ELISA: suitable, tissue culture: suitable, western blot: suitable
impurities
HIV I and HIVII, HCV and HBsAg, tested negative, ≤0.007% Fatty Acids
solubility
H2O: soluble 50 mg/mL, clear to slightly hazy
UniProt accession no.
storage temp.
2-8°C
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Gene Information
human ... ALB(213)
General description
Albumin is the most abundant plasma protein in human. It has a molecular weight of 66.5 kDa.
Application
Albumin from human serum has been used:
- as a carrier of CPT-11 (irinotecan, Campto) and SN-38 to investigate its binding to human plasma proteins
- to study the adsorption of water and acetonitrile (AN) vapor on a human serum albumin
- to study its effect on wound healing process
Biochem/physiol Actions
Le albumine sono proteine monomeriche solubili presenti nei fluidi e nei tessuti corporei degli animali e nei semi di alcune piante. L′albumina sierica svolge le funzioni di proteina carrier per gli steroidi, gli acidi grassi e gli ormoni tiroidei. Le albumine sieriche sono anche di vitale importanza nella regolazione delle pressioni colloido-osmotiche del sangue.
L′albumina sierica svolge le funzioni di proteina carrier per gli steroidi, gli acidi grassi e gli ormoni tiroidei ed è di vitale importanza nella regolazione delle pressioni colloido-osmotiche del sangue. È stato anche osservato che l′albumina si lega a sostanze esogene, farmaci in particolare (per es. ibuprofene, warfarin) influenzandone pesantemente la farmacocinetica. Lo stress ossidativo che determina modificazioni dello stato redox dell′albumina ha effetti molto variabili sulla sua funzione fisiologica.
Serum albumin primarily mediates divalent cation transportation, fatty acid and drug complex formation and transport. The albumin levels in the serum indicate the disease progression in advanced liver disease. Low body weight and decreased serum albumin is associated with colorectal cancer.
Preparation Note
Prepared from albumin (A1653)
Other Notes
Vedere maggiori informazioni sull′albumina sierica umana.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Questo articolo | |||
|---|---|---|---|
| description lyophilized powder, essentially fatty acid free | description lyophilized powder, ≥96% (agarose gel electrophoresis) | description lyophilized powder, low endotoxin | description Cellastim S™, recombinant, expressed in rice, lyophilized powder, suitable for cell culture, low endotoxin, ≥96% (SDS-PAGE) |
| biological source human | biological source human | biological source human | biological source human |
| technique(s) ELISA: suitable, western blot: suitable, tissue culture: suitable | technique(s) western blot: suitable, ELISA: suitable, tissue culture: suitable | technique(s) activity assay: suitable | technique(s) cell culture | mammalian: suitable |
| assay ≥96% (agarose gel electrophoresis) | assay ≥96% (agarose gel electrophoresis) | assay ≥96% (agarose gel electrophoresis) | assay ≥96% (SDS-PAGE) |
| Quality Level 300 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form lyophilized powder |
| impurities HIV I and HIVII, HCV and HBsAg, tested negative, ≤0.007% Fatty Acids | impurities HIV I and HIVII, HCV and HBsAg, tested negative | impurities ≤1.0 EU/mg endotoxin, HIV I and HIVII, HCV and HBsAg, tested negative | impurities ≤1 EU/mg protein |
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Classe di stoccaggio
11 - Combustible Solids
Che succede?
WGK 3
Punto di infiammabilità (°F)
Not applicable
Punto di infiammabilità (°C)
Not applicable
DPI (dispositivi di protezione individuale)
Eyeshields, Gloves
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What is the purpose of the charcoal purification step, and has it been verified that charcoal is not present in the final product? Additionally, how can it be ensured that components of the buffer used for lyophilization are not present in the final product if they are not tested for on the COA?
1 answer-
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