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70215

2,3-Naphthalenedicarboxaldehyde

suitable for fluorescence

Sinonimo/i:

NDA

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A voi/SKUDisponibilitàPrezzo
100 mg
Per conoscere la disponibilità, visualizza il carrello
CHF 254.00
500 mg
Per conoscere la disponibilità, visualizza il carrello
CHF 927.00
CHF 648.90

Informazioni su questo articolo

Formula condensata:
C10H6(CHO)2
Numero CAS:
7149-49-7
Peso molecolare:
184.19
UNSPSC Code:
12352108
NACRES:
NA.32
PubChem Substance ID:
329762349
MDL number:
MFCD00016618
Beilstein/REAXYS Number:
2207267
Form:
crystals

CHF 254.00

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form

crystals

Quality Segment

100

impurities

≤2% mono- and dicarboxylic acid (1H-NMR)

mp

131-133 °C (lit.), 132-135 °C

fluorescence

λex 420 nm; λem ~480 nm in 0.1 M borate pH 9.3 (after derivatization with glycine [~90 μM glycine, ~20 μM N-])

suitability

suitable for fluorescence

storage temp.

2-8°C

SMILES string

[H]C(=O)c1cc2ccccc2cc1C([H])=O

InChI

1S/C12H8O2/c13-7-11-5-9-3-1-2-4-10(9)6-12(11)8-14/h1-8H

InChI key

ZIPLKLQPLOWLTM-UHFFFAOYSA-N

General description

2,3-Naphthalenedicarboxaldehyde, also known as NDA, is a novel fluorescent derivatization agent. The fluorescence max. excitation of NDA is in the range of 424 nm and max. emission is achieved at 484nm.[1]

2,3-Naphthalenedicarboxaldehyde is a fluorescent derivatization agent of primary amines, amino acids, and small peptides. The reaction between the amino compounds and NDA results in highly fluorescent and stable derivative compounds.

Application

2,3-Naphthalenedicarboxaldehyde is used as a fluorescent labelling agent for quantification of Histamine in human immunoglobulin preparations.[1] NAD is used as a derivatization agent for glutathione to quantify protein glutathionylation.[2] It is a suitable reagent used for the development of fluorescence-based microtiter plate assay for γ-glutamylcyclotransferase.[3]

Features and Benefits

NDA based fluorescent assays have the following benefits over O-Phthalaldehyde (OPA):

  • High Reaction rate.
  • High Fluorescence quantum yield.
  • No uncommon excitation wavelength.
  • No side reactions.

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Questo articolo
7976046940N9158
2,3-Naphthalenedicarboxaldehyde suitable for fluorescence

Sigma-Aldrich

70215

2,3-Naphthalenedicarboxaldehyde

Ftaldialdeide suitable for fluorescence, ≥99.0% (HPLC)

Sigma-Aldrich

79760

Ftaldialdeide

6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester suitable for fluorescence, ≥75% (HPLC)

Sigma-Aldrich

46940

6-[Fluorescein-5(6)-carboxamido]hexanoic acid N-hydroxysuccinimide ester

N-(NBD-Aminolauroyl)ceramide ≥98%

Sigma-Aldrich

N9158

N-(NBD-Aminolauroyl)ceramide

Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

200

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

mp

131-133 °C (lit.), 132-135 °C

mp

54-56 °C

mp

-

mp

-

form

crystals

form

solid

form

solid

form

solid

fluorescence

λex 420 nm; λem ~480 nm in 0.1 M borate pH 9.3 (after derivatization with glycine [~90 μM glycine, ~20 μM N-])

fluorescence

λex 334 nm; λem 455 nm (Thiol Adduct), λex 340 nm; λem 450 nm in reaction buffer (with glycine)

fluorescence

λex 490 nm; λem 514 nm (pH 8.2), λex 491 nm; λem 515 nm in 0.1 M Tris pH 9.0

fluorescence

-

impurities

≤2% mono- and dicarboxylic acid (1H-NMR)

impurities

≤0.5% phthalic acid

impurities

-

impurities

-

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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