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40809

Purine nucleoside phosphorylase

recombinant, expressed in E. coli, ≥120 U/mL

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Informazioni su questo articolo

Numero CAS:
UNSPSC Code:
12352204
Numero CE:
MDL number:


recombinant

expressed in E. coli

form

buffered aqueous solution (100 mM phosphate buffer with 1 mM MgCl2)

specific activity

≥120 U/mL

storage temp.

−20°C

InChI

1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s1

InChI key

MRWXACSTFXYYMV-FDDDBJFASA-N

Application

Purine nucleoside phosphorylase is used to study nucleotide salvage pathways and purine metabolism[1]. It is used to study purine nucleoside phosphorylase deficiency and responsible PNP genetic mutations.

Biochem/physiol Actions

Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine[1]. Mutations in the PNP gene are responsible for purine nucleoside phosphorylase deficiency.

Other Notes

1 U will cause the phosphorolysis 1 μmol of inosine to hypoxanthine and ribose 1-phosphate per minute at pH 7.4 at 25°C


Classe di stoccaggio

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Questions

1–2 of 2 Questions  
  1. What is the source gene of the purine nucleoside phosphorylase, Product 40809?

    1 answer
    1. Per our supplier, the purine nucleoside phosphorylase,product 40809, is of bacterial origin, specifically from Enterobacter.

      Helpful?

  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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