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405M-1

FOXA1 (2F83) Mouse Monoclonal Antibody

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Informazioni su questo articolo

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
2F83, monoclonal
Application:
IHC (p)
Citations:
2
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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

2F83, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (405M-14), vial of 0.5 mL concentrate (405M-15), bottle of 1.0 mL predilute (405M-17), vial of 1.0 mL concentrate (405M-16), bottle of 7.0 mL predilute (405M-18)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

isotype

IgG1κ

control

breast carcinoma

shipped in

wet ice

storage temp.

2-8°C

visualization

nuclear

Gene Information

human ... FOXA1(3169)

General description

Forkhead box A1 (FOXA1), also known as hepatocyte nuclear factor 3 alpha(HNF3a), is a transcription factor expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. It has been reported to co-express with ER in breast carcinoma, predominantly in luminal subtype A.[1][2] FOXA1 expression has been identified in 42% - 75% of invasive carcinoma of the breast.[1][2] Of the FOXA1-positive breast invasive carcinomas, 83% were comprised of ER+/PR+/Her2+ luminal A subtype.[1] The results indicate that anti-FOXA1 is useful in the sub-classification of breast carcinoma.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

FOXA1 Positive Control Slides, Product No. 405S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: [email protected]

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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Questions

  1. Does the FOXA1 (2F83) antibody only react to human cells, or does it also react to mouse cells?

    1 answer
    1. Cell Marque IVD antibodies are only tested for use on human tissue in a clinical setting with immunohistochemistry only. No other methods such as Fluorescence or Flow Cytometry or western blot or other species such as mouse, rabbit, monkey, etc. have been qualified to work with those antibodies.

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