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363A-1

Sigma-Aldrich

PAX-8 Rabbit Polyclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

Ig fraction of antiserum

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (363A-14)
vial of 0.5 mL concentrate (363A-15)
bottle of 1.0 mL predilute (363A-17)
bottle of 7.0 mL predilute (363A-18)

Produttore/marchio commerciale

Cell Marque™

tecniche

immunohistochemistry: 1:25-1:100

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Informazioni sul gene

human ... PAX8(7849)

Categorie correlate

Descrizione generale

PAX-8 is a transcription factor expressed during the embryonic development of Müllerian organs,kidneys, and thyroid, with continued expression in some epithelial cell types of these maturetissues. PAX-8 is a useful marker for neoplasms of gynecologic, renal, and thyroidorigin. This antibody targets the N-terminus of the PAX-8 molecule. This section of the protein isshared with other PAX proteins such as PAX-5 and PAX-6; thus, some cross-reactivitywith these proteins may be observed as evidenced by the labeling of selected lymphocytes, andneuroendocrine cells.

Qualità


IVD
IVD
IVD
RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Ping Zhang et al.
Pathology international, 56(5), 240-245 (2006-05-04)
Thyroid transcription factor 1 (TTF1), thyroid transcription factor 2 (TTF2) and paired box gene 8 (Pax8) are demonstrated to play a crucial role for the differentiation and organogenesis of thyroid follicular cells. Their roles in thyroid carcinogenesis are not very
Biljana Pauzar et al.
Collegium antropologicum, 36 Suppl 2, 79-82 (2013-02-13)
US-guided fine needle aspiration cytology is currently the best diagnostic tool for thyroid nodules. However, it is not sensitive and specific enough for differentiating between benign and malignant follicular tumors. A potentially useful marker for this differentiation is the PAX8-PPARgamma
Tina Di Palma et al.
The Journal of biological chemistry, 278(5), 3395-3402 (2002-11-21)
Pax genes encode for transcription factors essential for tissue development in many species. Pax8, the only member of the family expressed in the thyroid tissue, is involved in the morphogenesis of the gland and in the transcriptional regulation of thyroid-specific
Control of sheath back bleeding: a simplified approach.
G I Gabliani et al.
Catheterization and cardiovascular diagnosis, 13(6), 427-427 (1987-11-01)
Nathan J Bowen et al.
Gynecologic oncology, 104(2), 331-337 (2006-10-27)
Epithelial ovarian carcinomas develop from ovarian surface epithelia that undergo complex differentiation to form distinguishable phenotypes resembling those of the epithelia of the female urogenital regions. While previous studies have implicated regulatory developmental homeobox (HOX) genes in this process, other
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