343M-9

TTF-1 (8G7G3/1) Mouse Monoclonal Antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: 8G7G3/1, monoclonal
• Descrizione: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (343M-94); vial of 0.5 mL concentrate (343M-95); bottle of 1.0 mL predilute (343M-97); vial of 1.0 mL concentrate (343M-96); bottle of 7.0 mL predilute (343M-98)
• Produttore/marchio commerciale: Cell Marque^™
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• Isotipo: IgG1
• Controllo: lung adenocarcinoma
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: nuclear
• Informazioni sul gene: human ... A1CF(29974)

Descrizione

Descrizione generale

Anti-TTF-1 (Thyroid Transcription Factor 1) is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the organs rather than thyroid, germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. TTF-1 labeling is also seen in thyroid and thyroid-derived tumors TTF-1 immunostaining is useful in the differentiation between pulmonary and nonpulmonary origin of adenocarcinomas in malignant effusions. TTF-1 staining is very reliable in discerning whether a brain metastasis has arisen from a pulmonary or nonpulmonary site, particularly when dealing with adenocarcinomas and large-cell carcinomas.

Thyroid transcription factor-1 (TTF-1) is a transcription factor that plays a role in regulating genes expressed within the thyroid, lungs, and brain. TTF-1 expression is present in normal thyroid epithelium and type II pneumocytes and nonciliated bronchiolar secretory cells of the lung. TTF-1 expression is seen in most primary lung and thyroid carcinomas, but rarely in other carcinomas. Anti-TTF-1 immunohistochemistry is useful for identifying carcinomas of thyroid and lung origin.

Qualità

IVD

IVD

IVD

RUO

Linkage

TTF-1 Positive Control Slides, Product No. 343S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

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Note legali

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