338R-2

TdT (EP266) Rabbit Monoclonal Primary Antibody

• Sinonimo/i: Terminal Deoxynucleotidyl Transferase
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: EP266, monoclonal
• Application: IHC (p)
• Citations: 4

Proprietà

• biological source: rabbit
• Quality Segment: 100, 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: EP266, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (338R-24), vial of 0.1 mL concentrate Research Use Only (338R-24-RUO), vial of 0.5 mL concentrate (338R-25), vial of 1.0 mL concentrate (338R-26), vial of 1.0 mL concentrate Research Use Only (338R-26-RUO), vial of 1.0 mL pre-dilute Research Use Only (338R-27-RUO), vial of 1.0 mL pre-dilute ready-to-use (338R-27), vial of 7.0 mL pre-dilute ready-to-use (338R-28), vial of 7.0 mL pre-dilute ready-to-use Research Use Only (338R-28-RUO)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)
• isotype: IgG
• control: thymus
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: nuclear
• Gene Information: human ... DNTT(1791)

Descrizione

General description

TdT (terminal deoxynucleotidyl transferase) is a template-independent DNA polymerase that adds nucleotides randomly to single-stranded DNA. This randomization plays a role in acquired immunity by increasing antigen receptor diversity and aiding in the generation of immunoglobulins and T cell antigen receptors.[1] TdT expression is characteristic of lymphoid progenitor cells in thymus and tonsils.[2] Anti-TdT is a useful marker for lymphoblastic lymphomas[3] and has been observed in some cases of acute myeloid leukemia.[4]

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note

IVD

IVD

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

TdT Positive Control Slides, Product No. 338S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections)

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Classe di stoccaggio: 12 - Non Combustible Liquids
• wgk: WGK 2