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Y0000220

Roxithromycin for system suitability

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Roxithromycin, Erythromycin 9-(-O-[2-methoxyethoxy]methyloxime)

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10 MG
CHF 135.00

CHF 135.00


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Cambia visualizzazione
10 MG
CHF 135.00

About This Item

Formula empirica (notazione di Hill):
C41H76N2O15
Numero CAS:
Peso molecolare:
837.05
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

CHF 135.00


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Grado

pharmaceutical primary standard

Famiglia di API

roxithromycin

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC3OC(C)CC(C3O)N(C)C)C(C)(O)CC(C)C(=N/OCOCCOC)\C(C)C(O)C1(C)O

InChI

1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/b42-31+
RXZBMPWDPOLZGW-FEMONOMJSA-N

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Roxithromycin for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Azioni biochim/fisiol

Semisynthetic erythromycin derivative. Impairs NADPH oxidase activation and alters translocation of its cytosolic components to the neutrophil membrane.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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A Markham et al.
Drugs, 48(2), 297-326 (1994-08-01)
Roxithromycin is a derivative of the macrolide antibacterial erythromycin with in vitro antibacterial activity resembling that of the parent compound. The drug has activity against some Staphylococcus spp., many Streptococcus spp., Moraxella (Branhamella) catarrhalis, Mycoplasma pneumoniae, Legionella pneumophila and Chlamydia
[Revaluation of current antimicrobials. Series 18: Roxithromycin].
Y Niki et al.
The Japanese journal of antibiotics, 47(10), 1275-1282 (1994-10-01)
[Roxithromycin (Forilin, Surlid)].
N H Eriksen et al.
Ugeskrift for laeger, 152(6), 411-412 (1990-02-05)
Ming Xue et al.
Analytical and bioanalytical chemistry, 412(1), 203-222 (2019-12-06)
This study examines an improved and simplified method for solid-phase extraction (SPE), which offers rapid and accurate determination and identification of 44 pharmaceutically active compounds using ultra-performance liquid chromatography (UPLC) and tandem mass spectrometry (MS/MS). The common active compounds include
E Bergogne-Bérézin
Presse medicale (Paris, France : 1983), 25(39), 1982-1988 (1996-12-14)
Macrolides, one of the oldest antibiotic classes, are widely used in out-patient, clinics and hospitals. The major improvement in developing newer derivatives concerns pharmacokinetic properties. Increased half-lives, persisting concentrations in tissues, interstitial fluids and macrophages confer upon newer macrolides significant

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