PHR8848

Cocaine hydrochloride

certified reference material, pharmaceutical secondary standard

• Sinonimo/i: Ecgonine methyl ester benzoate hydrochloride
• Formula empirica (notazione di Hill): C₁₇H₂₁NO₄ · HCl
• Numero CAS: 53-21-4
• Peso molecolare: 339.81
• Numero MDL: MFCD00058119
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• agenzia: traceable to USP 1143008
• Famiglia di API: cocaine
• applicazioni: pharmaceutical
• Temperatura di conservazione: -10 to -25°C
• Stringa SMILE: Cl.COC(=O)[C@H]1[C@H](C[C@@H]2CC[C@H]1N2C)OC(=O)c3ccccc3
• InChI: 1S/C17H21NO4.ClH/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11;/h3-7,12-15H,8-10H2,1-2H3;1H/t12-,13+,14-,15+;/m0./s1; PIQVDUKEQYOJNR-VZXSFKIWSA-N

Descrizione

Descrizione generale

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Azioni biochim/fisiol

Inhibits the dopamine, norepinephrine, and serotonin transporters with K_is of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS08
• Avvertenze: Danger
• Indicazioni di pericolo: H300 + H330,H336,H361d
• Consigli di prudenza: P202 - P260 - P264 - P270 - P271 - P304 + P340 + P310
• Classi di pericolo: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3
• Organi bersaglio: Central nervous system
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable