PHR1856

Quetiapine Fumarate

Pharmaceutical Secondary Standard; Certified Reference Material

• Sinonimo/i: Quetiapine hemifumarate salt, 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate, Quetiapine fumarate
• Formula empirica (notazione di Hill): C₂₁H₂₅N₃O₂S · 0.5C₄H₄O₄
• Numero CAS: 111974-72-2
• Peso molecolare: 441.54
• Numero MDL: MFCD03423782
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: certified reference material; pharmaceutical secondary standard
• Livello qualitativo: 300
• agenzia: traceable to Ph. Eur. Y0006157; traceable to USP 1592704
• Famiglia di API: quetiapine
• Stato: powder
• CdA: current certificate can be downloaded
• Confezionamento: pkg of 1 g
• applicazioni: pharmaceutical
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: OC(=O)\C=C\C(O)=O.OCCOCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OCCOCCN5CCN(CC5)C6=Nc7ccccc7Sc8ccccc68
• InChI: 1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+; ZTHJULTYCAQOIJ-WXXKFALUSA-N
• Informazioni sul gene: human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)

Descrizione

Descrizione generale

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Applicazioni

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Azioni biochim/fisiol

Quetiapine hemifumarate is a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.

Quetiapine hemifumarate is an atypical antipsychotic, a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAC0140 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Informazioni sulla sicurezza

• Pittogrammi: GHS07,GHS09
• Avvertenze: Warning
• Indicazioni di pericolo: H302,H400
• Consigli di prudenza: P273 - P301 + P312 + P330
• Classi di pericolo: Acute Tox. 4 Oral - Aquatic Acute 1
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable