F6145

Fenspiride hydrochloride

analytical standard, for drug analysis

• Sinonimo/i: 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride
• Formula empirica (notazione di Hill): C₁₅H₂₀N₂O₂ · HCl
• Numero CAS: 5053-08-7
• Peso molecolare: 296.79
• Numero CE: 225-752-9
• Numero MDL: MFCD00133315
• Codice UNSPSC: 41116107
• ID PubChem: 329799751

Proprietà

• Grado: analytical standard
• Livello qualitativo: 200
• Saggio: >99% (TLC)
• Stato: powder
• tecniche: HPLC: suitable; gas chromatography (GC): suitable
• Colore: white
• applicazioni: forensics and toxicology; pharmaceutical (small molecule); veterinary
• Formato: neat
• Stringa SMILE: Cl.O=C1NCC2(CCN(CCc3ccccc3)CC2)O1
• InChI: 1S/C15H20N2O2.ClH/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13;/h1-5H,6-12H2,(H,16,18);1H; FIKFLLIUPUVONI-UHFFFAOYSA-N
• Informazioni sul gene: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , HRH1(3269)

Descrizione

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Azioni biochim/fisiol

Bronchodilator with anti-inflammatory properties. Inhibits mucus secretion and reduces the release of tachykinins at a prejunctional level by its anti-muscarinic action. It also may be an antagonist at α adrenergic and H₁ histamine receptors.

Bronchodilator with anti-inflammatory properties. Inhibits mucus secretion and reduces the release of tachykinins at a prejunctional level by its anti-muscarinic action. It also may be an antagonist at α adrenergic and H₁ histamine receptors.
Fenspiride hydrochloride possesses anti-allergic and anti-bronchoconstrictive properties. It is used as a drug to treat inflammatory conditions of the upper and lower respiratory tracts.[1] Experimental studies state that fenspiride has an ability to reduce the development of myringosclerosis, possibly by restricting the formation of oxygen-derived free radicals.[1]

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H302 + H312 + H332
• Consigli di prudenza: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Classi di pericolo: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves