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C9481

Sigma-Aldrich

Carboxymethylcellulose sodium

Carboxymethylcellulose sodium

meets USP testing specifications, Medium viscosity

Sinonimo/i:

Carboxymethylcellulose sodium salt, Sodium carboxymethylcellulose

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500 G
CHF 399.00
1 KG
CHF 736.00

CHF 399.00


Spedizione prevista il22 maggio 2025


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Cambia visualizzazione
500 G
CHF 399.00
1 KG
CHF 736.00

About This Item

Numero CAS:
Numero MDL:
Codice UNSPSC:
12352201
NACRES:
NA.21

CHF 399.00


Spedizione prevista il22 maggio 2025


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agenzia

USP/NF
meets USP testing specifications

Livello qualitativo

Saggio

6.5-9.5% anhydrous basis (Sodium)

Stato

powder

Colore

light yellow

pH

(10 g/L68 °F neutral)

Viscosità

400-800 cP, 2 % in H2O(25 °C)(lit.)

Punto di fusione

> 300.05  °C ((> 572.09 °F ))

Solubilità

water: soluble

Stringa SMILE

[Na].OC(C(O)C(O)C=O)C(O)CO.OC(=O)C

InChI

1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);
DPXJVFZANSGRMM-UHFFFAOYSA-N

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Descrizione generale

Carboxymethylcellulose sodium is a viscous polysaccharide that belongs to a high molecular weight category. It has mucoadhesive property and is used during eye surgery. Carboxymethylcellulose sodium promotes re-epithelialization of the epithelial cells in corneal wounds.[1] It is useful for the study of attached cell and three-dimensional tissue culture models.[2]

Applicazioni

Carboxymethylcellulose sodium has been used as a vehicle for tamoxifen citrate,[3] sorafenib,[4] and savolitinib.[5] It has also been used as a component of serum-free medium (SFM) for the suspension of human umbilical vein endothelial spheroids.[6]
Useful for the study of attached cell and three-dimensional tissue culture models.

Altre note

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

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Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity
Simoes BM, et al.
Testing, 12(12), 1968-1977 (2015)
Vascular CXCR4 expression promotes vessel sprouting and sensitivity to sorafenib treatment in hepatocellular carcinoma
Xu J, et al.
Clinical Cancer Research, 23(15), 4482-4492 (2017)
Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing
Garrett Q, et al.
Investigative Ophthalmology & Visual Science, 48(4), 1559-1567 (2007)
The MET inhibitor AZD6094 (Savolitinib, HMPL-504) induces regression in papillary renal cell carcinoma patient-derived xenograft models
Schuller AG, et al.
Clinical Cancer Research, 21(12), 2811-2819 (2015)
Recent advances in modified cellulose for tissue culture applications
Courtenay J, et al.
Molecules (Basel), 23(3), 654-654 (2018)

Questions

1–5 of 5 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. I need this product information about Molecular weight. 분자량 범위 정보 필요

    1 answer
    1. The molecular weight of this product is 250 kDa.

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  4. What is the expiration/shelf life/retest date of this product? The Certificate of Analysis does not list any information about it for individual lots. Thank you!

    1 answer
    1. This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

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  5. I have a question regarding the degree of substitution of product C9481. As you know, the degree of substitution of CMC is an important characteristic. Have a wonderful day.

    1 answer
    1. The degree of substitution of this item is 0.7 (approximately 7 carboxymethyl groups per 10 anhydroglucose units).

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