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BCR050

Benzo[e]pyrene

BCR®, certified reference material

Sinonimo/i:

1,2-Benzpyrene, 4,5-Benzpyrene

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About This Item

Formula empirica (notazione di Hill):
C20H12
Numero CAS:
192-97-2
Peso molecolare:
252.31
Beilstein:
1911334
Numero CE:
205-892-7
Numero MDL:
MFCD00003605
Codice UNSPSC:
41116107
ID PubChem:
329774203
NACRES:
NA.24

Grado

certified reference material

agenzia

BCR®

Produttore/marchio commerciale

JRC

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

177-180 °C (lit.)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

c1ccc2c(c1)c3cccc4ccc5cccc2c5c34

InChI

1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H
TXVHTIQJNYSSKO-UHFFFAOYSA-N

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Categorie correlate

Risultati analitici

For more information please see:
BCR050

Note legali

BCR is a registered trademark of European Commission

Pittogrammi

Health hazardEnvironment
GHS08,GHS09

Avvertenze

Danger

Indicazioni di pericolo

H350,H410

Classi di pericolo

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number

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Saffar Mansoor et al.
Investigative ophthalmology & visual science, 51(5), 2601-2607 (2009-12-05)
To study the inhibitory effects of some agents or drugs (inhibitors) on benzo(e)pyrene (B(e)P)-induced cell death and apoptosis on human retinal pigment epithelial (ARPE-19) cells in vitro. ARPE-19 cells were pretreated with varying concentrations of different classes of inhibitors (calpain
W H Houser et al.
Molecular carcinogenesis, 5(3), 232-237 (1992-01-01)
In the rat, expression of the CYP1A1 gene is closely associated with arylhydrocarbon hydroxylase (AHH) enzyme activity. AHH is an inducile enzyme activity known to play an important role in the bioactivation of polycyclic aromatic hydrocarbons (PAHs) to mutagenic and
J A Gibbons et al.
Chemico-biological interactions, 83(3), 203-220 (1992-08-28)
The objective of this study was to examine the potential for a specific ligand of carcinogen binding protein (CBP) to induce changes in the overall character of hepatic microsomal cytochromes P-450 (P450) and to compare potential changes with those induced
D S Vienneau et al.
Cancer research, 55(5), 1045-1051 (1995-03-01)
UDP-glucuronosyltransferases (UGTs) are cytoprotective and may also be genoprotective. Since over 10% of the population have hereditary deficiencies in UGTs, this family of enzymes could constitute an important determinant of susceptibility to chemical carcinogenesis, teratogenesis, and neurodegeneration. Fibroblasts contain Phase
D F Lewis et al.
Toxicology letters, 71(3), 235-243 (1994-05-01)
The present studies were undertaken to provide a rationale for the observation that benzo(a)pyrene and 2-acetylaminofluorene induce the hepatic CYP1A1 protein, whereas their non-carcinogenic isomers benzo(e)pyrene and 4-acetylaminofluorene are, at best, relatively very weak inducers. Using amino acid sequence alignment
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