60063

Potassium antimonyl tartrate trihydrate

purum p.a., 99.0-103% (RT)

• Sinonimo/i: Antimony potassium tartrate trihydrate, Tartar emetic
• Formula empirica (notazione di Hill): C₈H₄K₂O₁₂Sb₂ · 3H₂O
• Numero CAS: 28300-74-5
• Peso molecolare: 667.87
• Numero CE: 234-293-3
• Numero MDL: MFCD00167056
• Codice UNSPSC: 12352100
• ID PubChem: 57651716
• NACRES: NA.21

Proprietà

• Grado: purum p.a.
• Livello qualitativo: 200
• Saggio: 99.0-103% (RT)
• Perdita: ≤2.7% loss on drying
• Punto di fusione: ≥300 °C (lit.)
• Anioni in tracce: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤500 mg/kg
• Cationi in tracce: Ca: ≤50 mg/kg; Cd: ≤50 mg/kg; Co: ≤50 mg/kg; Cu: ≤50 mg/kg; Fe: ≤50 mg/kg; Na: ≤500 mg/kg; Ni: ≤50 mg/kg; Pb: ≤50 mg/kg; Zn: ≤50 mg/kg
• Stringa SMILE: O.O.O.[K+].[K+].O=C1O[Sb-]23OC1C4O[Sb-]5(OC(C(O2)C(=O)O3)C(=O)O5)OC4=O
• InChI: 1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4; WBTCZEPSIIFINA-UHFFFAOYSA-J

Descrizione

Descrizione generale

Potassium antimonyl tartrate trihydrate is a trivalent antimony compound. It has been reported to be a leishmanicidal compound and exhibits more toxic action than pentavalent antimony (Pentostam) against Leishmania species.[1][2] Three-dimensional X-ray and white radiation neutron diffraction methods have been reported to investigate the crystal structure of its optically active form (dipotassium di-μ-d-tartrato (4)-bis(antimonate(III)) trihydrate). Unit cell dimensions reported were: a = 11.192(2), b = 11.696(3), and c = 25.932(5)Å.[3]

Applicazioni

Potassium antimonyl tartrate trihydrate may be used as an Sb(III)-containing drug to investigate its ability to induce cell death associated with DNA fragmentation in axenic amastigotes of Leishmania infantum.[4]

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS09
• Avvertenze: Danger
• Indicazioni di pericolo: H301,H315,H317,H332,H411
• Consigli di prudenza: P261 - P273 - P280 - P301 + P310 - P302 + P352 - P304 + P340 + P312
• Classi di pericolo: Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Skin Irrit. 2 - Skin Sens. 1
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves