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49322

Sigma-Aldrich

NMP

puriss. p.a., ≥99.0% (GC)

Sinonimo/i:

1-metil-2-pirrolidone, N-metil-2-pirrolidone, NMP

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About This Item

Formula empirica (notazione di Hill):
C5H9NO
Numero CAS:
872-50-4
Peso molecolare:
99.13
Beilstein:
106420
Numero CE:
212-828-1
Numero MDL:
MFCD00003193
Codice UNSPSC:
12352005
ID PubChem:
329757410
Prezzi e disponibilità al momento non sono disponibili

Nome del prodotto

1-metil-2-pirrolidinone, puriss. p.a., ≥99.0% (GC)

Densità del vapore

3.4 (vs air)

Tensione di vapore

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

Grado

puriss. p.a.

Saggio

≥99.0% (GC)

Stato

liquid

Temp. autoaccensione

518 °F

Limite di esplosione

9.5 %

tecniche

GC/GC: suitable

Impurezze

≤0.1% water

Indice di rifrazione

n20/D 1.47 (lit.)
n20/D 1.470

pH

7.7-8

P. ebollizione

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

Punto di fusione

−24 °C (lit.)

Densità

1.028 g/mL at 25 °C (lit.)

Cationi in tracce

Ca: ≤5 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤20 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Na: ≤20 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Zn: ≤1 mg/kg

Stringa SMILE

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
SECXISVLQFMRJM-UHFFFAOYSA-N

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Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Danger

Indicazioni di pericolo

H315,H319,H335,H360D

Classi di pericolo

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

195.8 °F - Pensky-Martens closed cup

Punto d’infiammabilità (°C)

91 °C - Pensky-Martens closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

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Certificati d'analisi (COA)

Lot/Batch Number

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B A Jönsson et al.
Journal of chromatography. B, Biomedical sciences and applications, 694(2), 351-357 (1997-07-04)
A method for simultaneous determination of 5-hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide in urine is described. These compounds are metabolites of N-methyl-2-pyrrolidone, a powerful and widely used organic solvent. 5-Hydroxy-N-methylpyrrolidone and 2-hydroxy-N-methylsuccinimide were purified from urine by adsorption to a C8 solid-phase extraction
K J Brodbeck et al.
Journal of controlled release : official journal of the Controlled Release Society, 62(3), 333-344 (1999-10-21)
The role of solvent properties and bath-side composition on the phase inversion dynamics and in vitro protein release kinetics of polylactic-co-glycolic acid (PLGA) solutions has been examined using dark ground imaging, in vitro release rate, and SEM techniques. Thermodynamic phase
Ajit Dhananjay Jagtap et al.
European journal of medicinal chemistry, 85, 268-288 (2014-08-05)
A series of 6-acylureido derivatives containing a 3-(pyrrol-2-ylmethylidene)indolin-2-one scaffold were synthesized as potential dual Aurora B/FLT3 inhibitors by replacing the 6-arylureido moiety in 6-arylureidoindolin-2-one-based multi-kinase inhibitors. (Z)-N-(2-(pyrrolidin-1-yl)ethyl)-5-((6-(3-(2-fluoro-4-methoxybenzoyl)ureido)-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide (54) was identified as a dual Aurora B/FLT3 inhibitor (IC50 = 0.4 nM and 0.5 nM, respectively).
Hsiao-Chun Wang et al.
European journal of medicinal chemistry, 84, 312-334 (2014-07-19)
Bioisosteric replacement of acylureido moiety in 6-acylureido-3-pyrrolylmethylidene-2-oxoindoline derivatives resulted in a series of malonamido derivatives with indolin-2-one scaffold (11-14). Further conformational restrictions of the malonamido moiety led to 2-oxo-1,2-dihydropyridine (21-25) or a 4-oxo-1,4-dihydropyridine derivatives (31-36). 4-Oxo-1,4-dihydropyridine derivatives were more potent
Yanying Lu et al.
Nanoscale, 7(6), 2770-2776 (2015-01-15)
In this paper, we report on the synthesis of micro-nanostructured CuO/C spheres by aerosol spray pyrolysis and their application as high-performance anodes in sodium-ion batteries. Micro-nanostructured CuO/C spheres with different CuO contents were synthesized through aerosol spray pyrolysis by adjusting
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