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46127

Sigma-Aldrich

7-Ethoxy-4-(trifluoromethyl)coumarin

suitable for fluorescence, ≥98.0% (TLC)

Sinonimo/i:

Ethyl 4-(trifluoromethyl)umbelliferyl ether

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About This Item

Formula empirica (notazione di Hill):
C12H9F3O3
Numero CAS:
115453-82-2
Peso molecolare:
258.19
Beilstein:
8555209
Numero MDL:
MFCD00467588
Codice UNSPSC:
12352204
ID PubChem:
24869840

Saggio

≥98.0% (TLC)

Solubilità

DMF: soluble
DMSO: soluble
methanol: soluble

Fluorescenza

λex 333 nm; λem 415 nm in methanol

Compatibilità

suitable for fluorescence

Stringa SMILE

CCOc1ccc2c(OC(=O)C=C2C(F)(F)F)c1

InChI

1S/C12H9F3O3/c1-2-17-7-3-4-8-9(12(13,14)15)6-11(16)18-10(8)5-7/h3-6H,2H2,1H3
OLHOIERZAZMHGK-UHFFFAOYSA-N

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Altre note

Substrate for monitoring the activity of cytochrome P450

Sostituito da

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number

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Maori Mitsuda et al.
Protein expression and purification, 46(2), 401-405 (2005-11-29)
Improvement of CYP2B6 expression was examined by co-expression with molecular chaperones GroES/EL. Although a CO-reduced difference spectrum was not detected in Escherichia coli transformed only by the CYP2B6-expressing vector, co-expression of GroES/EL resulted in high-level expression which reached over 2000
Thomas Van Leeuwen et al.
Pest management science, 62(5), 425-433 (2006-03-22)
Tetranychus urticae Koch has recently developed resistance to chlorfenapyr in Australia and Japan, but no attempt has yet been made to describe the biochemical mechanisms involved in chlorfenapyr resistance. In this study a laboratory-selected chlorfenapyr-resistant strain was investigated. Resistance to
Shih-Feng Lan et al.
Toxicology in vitro : an international journal published in association with BIBRA, 24(4), 1314-1323 (2010-02-23)
In this study, we have evaluated the use of ultra-sterile alginate hydrogels encapsulated with HepG2 liver cells for applications in high throughput drug screening. We have studied the cellular viability and metabolic capacity of the encapsulated cells in two different
Emily E Scott et al.
Chemical research in toxicology, 15(11), 1407-1413 (2002-11-20)
Until recently, all known structures of bacterial cytochromes P450 suggested that substrate access to the buried active site occurred via the F-G region, a surface loop distal to the heme cavity. However, the structure of P450 51 indicates a large
Chitra Sridar et al.
The Journal of pharmacology and experimental therapeutics, 301(3), 945-952 (2002-05-23)
Tamoxifen is primarily used in the treatment of breast cancer. It has been approved as a chemopreventive agent for individuals at high risk for this disease. Tamoxifen is metabolized to a number of different products by cytochrome P450 enzymes. The
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