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Tenuazonic acid

analytical standard

Sinonimo/i:

(5S)-3-Acetyl-1,5-dihydro-4-hydroxy-5-[(1S)-1-methylpropyl]-2H-pyrrol-2-one, (S)-3-Acetyl-5-(S)-sec-butyltetramic acid, (S)-3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one

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100 μG
CHF 807.00

CHF 807.00


Spedizione prevista il14 maggio 2025


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Cambia visualizzazione
100 μG
CHF 807.00

About This Item

Formula empirica (notazione di Hill):
C10H15NO3
Numero CAS:
Peso molecolare:
197.23
Beilstein:
3589518
Numero MDL:
Codice UNSPSC:
85151701
ID PubChem:
NACRES:
NA.24

CHF 807.00


Spedizione prevista il14 maggio 2025


Richiedi un ordine bulk

Grado

analytical standard

Livello qualitativo

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

cleaning products
cosmetics
food and beverages
personal care

Formato

neat

Temperatura di conservazione

−20°C

Stringa SMILE

CC[C@H](C)[C@@H]1NC(=O)C(C(C)=O)=C1O

InChI

1S/C10H15NO3/c1-4-5(2)8-9(13)7(6(3)12)10(14)11-8/h5,8,13H,4H2,1-3H3,(H,11,14)/t5-,8-/m0/s1
CEIZFXOZIQNICU-XNCJUZBTSA-N

Descrizione generale

Tenuazonic acid is a biologically active compound and its mode of action involves the inhibition of protein biosynthesis.[1]
Tenuazonic acid is a mycotoxin, which belongs to the class of tetramic acids, the largest family of natural products.[2] It is generally isolated from phytopathogenic fungal species like Alternaria alternata, A. longipes and A. tenuissima.[2]

Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tenuazonic acid may be used as an analytical reference standard for the quantification of the analyte in the following:
  • Cornflakes using high-performance liquid chromatography (HPLC) technique.[3]
  • Human urine samples using isotope dilution assay method and liquid chromatography coupled to a hybrid triple quadrupole/linear ion trap mass spectrometer.[4]
  • Cereals using high-performance liquid chromatography–electrospray ionization ion-trap multistage mass spectrometry (HPLC- ESI ion-trap (IT) MS2). ESI Fourier transform-ion cyclotron resonance tandem mass spectrometry (FTICR-MS2) technique is used for product characterization, post derivatization with 2,4-dinitrophenylhydrazine.[1]

Ricostituzione

Dried down, ~100 μg/mL after reconstitution with 1 mL of water

Risultati analitici

purity : ≥96.0% (HPLC)

Pittogrammi

Skull and crossbones

Avvertenze

Danger

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Acute Tox. 3 Oral

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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Andrea Patriarca et al.
International journal of food microbiology, 291, 135-143 (2018-12-01)
The group of the small-spored Alternaria species is particularly relevant in foods due to its high frequency and wide distribution in different crops. These species are responsible for the accumulation of mycotoxins and bioactive secondary metabolites in food. The taxonomy
Recent advances in tenuazonic acid as a potential herbicide
Chen S and Qiang S
Pesticide Biochemistry and Physiology (2017)
Determination of tenuazonic acid in human urine by means of a stable isotope dilution assay
Asam S, et al.
Analytical and Bioanalytical Chemistry, 405(12), 4149-4158 (2013)
Simultaneous determination of ochratoxin A and cyclopiazonic, mycophenolic, and tenuazonic acids in cornflakes by solid-phase microextraction coupled to high-performance liquid chromatography
Aresta A, et al.
Journal of Agricultural and Food Chemistry, 51(18), 5232-5237 (2003)
Shiguo Chen et al.
Plant physiology and biochemistry : PPB, 52, 38-51 (2012-02-07)
3-Acetyl-5-isopropyltetramic acid (3-AIPTA), a derivate of tetramic acid, is responsible for brown leaf-spot disease in many plants and often kills seedlings of both mono- and dicotyledonous plants. To further elucidate the mode of action of 3-AIPTA, during 3-AIPTA-induced cell necrosis

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