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11709
Barbituric acid
Barbituric acid
for spectrophotometric det. of cyanide, ≥99.5%
Sinonimo/i:
2,4,6-Trihydroxypyrimidine, Malonylurea
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100 G
CHF 499.00
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100 G
CHF 499.00
About This Item
Formula empirica (notazione di Hill):
C4H4N2O3
Numero CAS:
Peso molecolare:
128.09
Beilstein:
120502
Numero CE:
Numero MDL:
Codice UNSPSC:
12000000
ID PubChem:
NACRES:
NA.21
Prodotti consigliati
Livello qualitativo
Saggio
≥99.5% (HPLC)
≥99.5%
Stato
solid
Qualità
for spectrophotometric det. of cyanide
tecniche
UV/Vis spectroscopy: suitable
Residuo alla calcinazione
≤0.05%
Punto di fusione
248-252 °C (dec.) (lit.)
Anioni in tracce
chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤500 mg/kg
Cationi in tracce
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
Mg: ≤10 mg/kg
Mn: ≤5 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg
Stringa SMILE
O=C1CC(=O)NC(=O)N1
InChI
1S/C4H4N2O3/c7-2-1-3(8)6-4(9)5-2/h1H2,(H2,5,6,7,8,9)
HNYOPLTXPVRDBG-UHFFFAOYSA-N
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Categorie correlate
Descrizione generale
Barbituric acid is also known as malonurea or 6-hydroxyuracil, it is an odourless powder and is soluble in water. It has a very high pharmacological activity and can be used to synthesize addition derivatives of it, to be used in novel drug discovery. It basically acts on the central nervous system (CNS) depressants, thereby possessing a wide range from mild sedation to total anaesthesia.[1]
Applicazioni
Barbituric acid with aromatic aldehydes was used in an experimental study, meant to demonstrate the increased efficiency of Knoevenagel condensation reaction for barbituric acid and various aromatic aldehydes on basic alumina, in the absence of organic solvents under microwave irradiation.[2] It may also be used in electrochemical oxidation of iodine, using cyclic voltammetry and controlled-potential coulometry.[3]
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
302.0 °F - closed cup
Punto d’infiammabilità (°C)
150.00 °C - closed cup
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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I clienti hanno visto anche
Bioactive Heterocyclic Compound Classes.
Clemens L and Dinges J.
Pharmaceutics, 24-27 (2012)
Electrochemical study of iodide in the presence of barbituric acid. Application to coulometric titration of barbituric acid.
Nematollahi D and Hesari M
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 70 (1), 7-11 (2001)
Microwave enhanced knoevenagel condensation of barbituric acid with aromatic aldehydes on basic alumina.
Khalafi NA and Hashemi A.
Iranian Journal of Chemistry and Chemical Engineering, 20 (1), 9-11 (2001)
David C Chiara et al.
The Journal of biological chemistry, 288(27), 19343-19357 (2013-05-17)
GABA type A receptors (GABAAR), the brain's major inhibitory neurotransmitter receptors, are the targets for many general anesthetics, including volatile anesthetics, etomidate, propofol, and barbiturates. How such structurally diverse agents can act similarly as positive allosteric modulators of GABAARs remains
Szilvia Hajdok et al.
The Journal of organic chemistry, 74(19), 7230-7237 (2009-09-11)
The laccase-catalyzed reaction between catechols and heterocyclic 1,3-dicarbonyls (pyridinones, quinolinones, thiocoumarins) using aerial oxygen as the oxidant delivers benzofuropyridinones, benzofuroquinolinones, and thiocoumestans in a simple fashion, highly regioselectively with yields ranging from 55 to 98%. With barbituric acid derivatives the
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