Urokinase Plasminogen Acitivator is a serine protease (SERPIN) that converts plasminogen into the active protease plasmin. UPA is secreted from cells in as the inactive 52 kDa single chain precursor which is activated to the two chain form consisting of an alpha and beta chain.MAB7776 is specific for Human uPA, other species not tested.
Immunogeno
Amino Terminal Fragment of uPA
Epitope: N-terminus fragment
Applicazioni
Detect Urokinase using this Anti-Urokinase Antibody, N-terminus fragment, clone 2G6.2 validated for use in ELISA & WB.
Research Category Metabolism
Research Sub Category Enzymes & Biochemistry
Western blot: 1:1000-1:3000
ELISA
Optimal working dilutions must be determined by end user.
Stato fisico
Format: Purified
Purified immunoglobulin. Liquid in 0.02 M phosphate buffer containing 0.25 M NaCl2 and 0.1% NaN3.
Stoccaggio e stabilità
Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months.
Altre note
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Note legali
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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Cervical cancer remains a major health threat. Urokinase serves as a marker of metastatic tumors. The present study aimed to determine whether the expression levels of urokinase plasminogen activator (uPA) and urokinase plasminogen activator receptor (uPAR), before and during the
SOX9 encodes a transcription factor that governs cell fate specification throughout development and tissue homeostasis. Elevated SOX9 is implicated in the genesis and progression of human tumors by increasing cell proliferation and epithelial-mesenchymal transition. We found that in response to
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