14-477-M
Cdk5/p35 Protein, active, 10 µg
Active complex of recombinant full length human Cdk5 containing & N-terminal His6-tag & recombinant full-length human p35 containing an N-terminal GST-tag, for use in Kinase Assays.
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About This Item
Codice UNSPSC:
12352202
eCl@ss:
32160405
NACRES:
NA.26
Prodotti consigliati
Origine biologica
human
Livello qualitativo
Ricombinante
expressed in baculovirus infected Sf21 cells
PM
Mw 34 kDa (cdk5)
Mw 61 kDa (p35 with GST-tag)
Produttore/marchio commerciale
Upstate®
tecniche
activity assay: suitable (kinase)
N° accesso NCBI
N° accesso UniProt
Descrizione generale
Complex of recombinant fulllength human cdk5 containing and N-terminal His6-tag and recombinant full-length human p35 containing an N-terminal GST-tag
Product Source: Both are expressed by baculovirus in Sf21 insect cells
Azioni biochim/fisiol
Protein Target: CDK5/p35
Target Sub-Family: CMGC
Confezionamento
Also available in 250μg size as catalog # 14-477M - Call for pricing and availability.
Qualità
routinely evaluated by phosphorylation of Histone H1
Stato fisico
Ni-NTA agarose
Stoccaggio e stabilità
1 year at -70°C
Altre note
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Note legali
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Certificati d'analisi (COA)
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Ward G Walkup et al.
The Journal of biological chemistry, 290(8), 4908-4927 (2014-12-24)
synGAP is a neuron-specific Ras and Rap GTPase-activating protein (GAP) found in high concentrations in the postsynaptic density (PSD) fraction from the mammalian forebrain. We have previously shown that, in situ in the PSD fraction or in recombinant form in
Ward G Walkup et al.
eLife, 5 (2016-10-21)
SynGAP is a Ras/Rap GTPase-activating protein (GAP) that is a major constituent of postsynaptic densities (PSDs) from mammalian forebrain. Its α1 isoform binds to all three PDZ (PSD-95, Discs-large, ZO-1) domains of PSD-95, the principal PSD scaffold, and can occupy
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