1.01736
OSTEOMOLL®
Solution for rapid decalcification (with fixation) for histology
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Informazioni su questo articolo
Quality Segment
form
liquid
IVD
for in vitro diagnostic use
color
blue
pH
<1 (20 °C in H2O)
density
1.10 g/mL at 20 °C
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
15-25°C
General description
Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT® (Product number 1.01728) can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL®, can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and hydrochloric acid. The amount of OSTEOMOLL® needed is dependent upon on the size, type and thickness of the material. A 30 ml portion of OSTEOMOLL®, which should completely cover the material, can be used twice if the solution is still clear and not contaminated.
The material must first be cut to a thickness of max. 5 mm and an area of 6 cm2 (= max. Embedding cassette size). Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT® is color-coded yellow, OSTEOMOLL® is color-coded blue. Whereby OSTEOSOFT® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL® will be used for tissues that are not destined for antibody analysis.
Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. The quantity of OSTEOMOLL® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.
Analysis Note
Legal Information
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Questo articolo | |||
|---|---|---|---|
| Quality Level 400 | Quality Level 400 | Quality Level 400 | Quality Level 400 |
| form liquid | form liquid | form liquid | form liquid |
| application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) diagnostic assay manufacturing | application(s) clinical testing |
| pH <1 (20 °C in H2O) | pH 7.0-7.3 (20 °C in H2O) | pH 6.7-7.1 ( in H2O) | pH - |
| density 1.10 g/mL at 20 °C | density 1.10 g/mL at 20 °C | density 1.017 g/cm3 at 20 °C | density 1.18 g/cm3 at 20 °C |
| color blue | color dark red | color colorless | color - |
signalword
Danger
Hazard Classifications
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Classe di stoccaggio
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificati d'analisi (COA)
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