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T-004

Supelco

(±)-11-nor-9-Carboxy-Δ9-THC-D3 solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C21H25O4D3
Numero CAS:
Peso molecolare:
347.46
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

certified reference material

Forma fisica

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

drug control

psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)

Concentrazione

100 μg/mL in methanol

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

cannabis testing
forensics and toxicology

Formato

single component solution

Temperatura di conservazione

2-8°C

Stringa SMILE

OC1=C2C3C(CCC(C(O)=O)=C3)C(C)(C)OC2=CC(CCCCC([2H])([2H])[2H])=C1

InChI

1S/C21H28O4/c1-4-5-6-7-13-10-17(22)19-15-12-14(20(23)24)8-9-16(15)21(2,3)25-18(19)11-13/h10-12,15-16,22H,4-9H2,1-3H3,(H,23,24)/i1D3
YOVRGSHRZRJTLZ-FIBGUPNXSA-N

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Descrizione generale

11-nor-9-Carboxy-Δ9-THC, also known as THC acid, is the main secondary metabolite of Δ9-THC found in urine or blood of cannabis users. This internal standard is applicable for numerous applications in GC/MS or LC/MS testing from forensic analysis and clinical toxicology to urine drug testing and isotope dilution methods.

Applicazioni


  • Cannabis Use and Biomarkers of Inflammation, Immune Activation, and Microbial Translocation in Persons with HIV: This study examines the relationship between cannabis use and various health indicators in HIV-positive individuals. The use of cannabinoid metabolites like 11-nor-9-Carboxy-Δ⁹-THC in such research is critical for understanding the impact of cannabis on immune health (Okafor et al., 2024).

  • Postmortem redistribution of cannabinoids: Statistical analysis of a novel dataset and meta-analysis: This research investigates how cannabinoids, including THC and its metabolites, are distributed in the body postmortem. This is important for forensic sciences, particularly in determining the time and amount of substance use before death (Tascon et al., 2023).

  • Integrative Analysis of Proteome-wide Association Studies and Functional Enrichment Analysis to Identify Genes and Chemicals Associated with Alcohol Dependence: This study utilizes advanced proteomic and genomic analysis techniques to link chemical exposure, including cannabis metabolites, to genetic markers of alcohol addiction (Zhang et al., 2023).

  • Analysis, occurrence, and consumption of substances with abuse potential in Xinjiang, China, from 2021 to 2022: Provides insights into the usage patterns of psychoactive substances including cannabinoids, contributing to public health and regulatory strategies (Zhao et al., 2023).

  • Maternal and Fetal Exposure to (-)-Δ(9)-tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice Is Differentially Impacted by P-glycoprotein and Breast Cancer Resistance Protein: Explores how drug transporters affect the placental transfer of cannabinoids, which is crucial for understanding the risks associated with prenatal exposure (Chen et al., 2023).


Note legali

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Organi bersaglio

Eyes,Central nervous system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup


Certificati d'analisi (COA)

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Michal P Dybowski et al.
Forensic toxicology, 36(2), 415-423 (2018-07-03)
Analysis of drugs and their metabolites in biofluids usually demands the application of sample preparation methods that allow for full isolation of analyzed substances from the matrix. The purpose of this study was to develop a method using the QuEChERS

Articoli

Analysis of Tetrahydrocannabinol (THC) and Carboxytetrahydrocannabinol (THCCOOH) in Surface Waters by SPME and GC/MS

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