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N-031

Supelco

Norfentanyl oxalate solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Formula empirica (notazione di Hill):
C14H20N2O · C2H2O4
Numero CAS:
1211527-24-0
Peso molecolare:
322.36
Numero CE:
200-659-6
Numero MDL:
MFCD08272799
Codice UNSPSC:
41116107
ID PubChem:
329818426
NACRES:
NA.24
Prezzi e disponibilità al momento non sono disponibili

Grado

certified reference material

Stato

liquid

Caratteristiche

Snap-N-Spike®/Snap-N-Shoot®

Confezionamento

ampule of 1 mL

Produttore/marchio commerciale

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland)

Concentrazione

1.0 mg/mL in methanol (as free base)

tecniche

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

applicazioni

forensics and toxicology

Formato

single component solution

Temperatura di conservazione

−20°C

Stringa SMILE

OC(=O)C(O)=O.CCC(=O)N(C1CCNCC1)c2ccccc2

InChI

1S/C14H20N2O.C2H2O4/c1-2-14(17)16(12-6-4-3-5-7-12)13-8-10-15-11-9-13;3-1(4)2(5)6/h3-7,13,15H,2,8-11H2,1H3;(H,3,4)(H,5,6)
OLFNESLXXQCODF-UHFFFAOYSA-N

Descrizione generale

Norfentanyl is a major urinary metabolite of fentanyl, a potent synthetic analgesic sold under various trade names including Sublimaze, Duragesic®, Actiq®, and Fentora®. This Certified Spiking Solution® is suitable for numerous GC/MS or LC/MS testing applications from clinical toxicology and forensic analysis to urine drug testing and pain prescription monitoring.

Note legali

Actiq is a registered trademark of Anesta Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Duragesic is a registered trademark of Johnson & Johnson
Fentora is a registered trademark of Cima Labs, Inc.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Avvertenze

Danger

Indicazioni di pericolo

H225,H301 + H311 + H331,H334,H370

Classi di pericolo

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - Resp. Sens. 1 - STOT SE 1

Organi bersaglio

Eyes,Central nervous system

Codice della classe di stoccaggio

3 - Flammable liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

49.5 °F - closed cup

Punto d’infiammabilità (°C)

9.7 °C - closed cup

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Certificati d'analisi (COA)

Lot/Batch Number

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D E Feierman
Anesthesia and analgesia, 82(5), 936-941 (1996-05-01)
The metabolism of fentanyl was investigated using rat liver microsomes to determine whether fentanyl is metabolized by rat liver microsomal cytochrome P450 and, if so, which isoform is responsible for the metabolism. Microsomes isolated from rats pretreated with phenobarbital were
Nadine F J Van Nimmen et al.
Journal of clinical pharmacology, 50(6), 667-678 (2010-01-26)
Delivery rates and plasma concentrations vary among patients treated with fentanyl patches. Absorption and urinary excretion characteristics of fentanyl were studied in patients undergoing palliative care. Almost 500 patches were analyzed for residual fentanyl content. Fentanyl and norfentanyl levels were
Alphonse Poklis et al.
Journal of analytical toxicology, 28(6), 422-425 (2004-11-02)
A study of the urinary concentration of fentanyl (F) and its major metabolite norfentanyl (NF) in chronic pain patients treated with the Duragesic continuous release transdermal patches is presented. These patches are available in 10, 20, 30, and 40 cm(2)
Henry J Carson et al.
Legal medicine (Tokyo, Japan), 12(3), 157-159 (2010-04-07)
We recently encountered a subject who died from an uncommon misuse of a fentanyl transdermal patch, chewing, followed by complications of aspiration of the patch. We report this case to alert medical examiners to the troubling trend of increased fentanyl
D E Feierman et al.
Drug metabolism and disposition: the biological fate of chemicals, 24(9), 932-939 (1996-09-01)
The microsomal metabolism of fentanyl, a synthetic opioid commonly used in anesthesia, was investigated in human liver. Incubation of fentanyl with human hepatic microsomes fortified with NADPH resulted in the formation of a single major metabolite, namely norfentanyl, as determined
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Questions

  1. I'm interested in Fentanyl abuse test using urine specimen. Would this product work as positive control for this diagnostic test?

    1 answer

    1. Norfentanyl is a major urinary metabolite of fentanyl, a potent synthetic analgesic sold under various trade names including Sublimaze, Duragesic®, Actiq®, and Fentora®. Therefore, this Certified Spiking Solution is suitable for testing applications from clinical toxicology and forensic analysis to urine drug testing. So it can be used as a positive control for urinal drug testing.

      Helpful?

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