850156P

18:1 PI(3,4,5)P3

1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′,5′-trisphosphate) (ammonium salt), powder

• Sinonimo/i: 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-[phosphoinositol-3,4,5-trisphosphate] (ammonium salt); PIP3[3′,4′,5′](18:1(9Z)/18:1(9Z))
• Formula empirica (notazione di Hill): C₄₅H₉₈N₄O₂₂P₄
• Numero CAS: 799268-57-8
• Peso molecolare: 1171.17
• Codice UNSPSC: 51191904
• NACRES: NA.25

Proprietà

• Saggio: >99% (TLC)
• Stato: powder
• Confezionamento: pkg of 1 × 100 μg (with stopper and crimp cap (850156P-100ug)); pkg of 1 × 500 μg (with stopper and crimp cap (850156P-500ug))
• Produttore/marchio commerciale: Avanti Research^™ - A Croda Brand 850156P
• Tipo di lipide: cardiolipins; phospholipids
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@@](COP(O[C@H]1[C@H](O)[C@@H](OP([O-])(O)=O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+].[NH4+]
• InChI: CTYBALUTLRWYAN-CJXCTDJBSA-N

Descrizione

Descrizione generale

Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.

Phosphatidylinositol is a structural phospholipid.[1] Phosphatidylinositol phosphate (PIP) is located in the plasma membrane.[2]

Applicazioni

18:1 PI(3,4,5)P3 is suitable to use in lipid stock preparation to form mixed micelles.[3] It has also been used:

• in the preparation of planar-supported lipid bilayers (SLBs)[4]
• in supplementing or enriching phagocyte membrane[5]
• in liposome preparation[6]

Azioni biochim/fisiol

Phosphoinositol-containing sphingolipids can induce ATPase at lower levels when compared to glycerophospholipids.[2]

Confezionamento

2 mL Amber Serum Vial with Stopper and Crimp Cap (850156P-100ug)

2 mL Amber Serum Vial with Stopper and Crimp Cap (850156P-500ug)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): No data available
• Punto d’infiammabilità (°C): No data available