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810193C

Avanti

16:0-12:0 NBD PS

Avanti Research™ - A Croda Brand 810193C

Sinonimo/i:

1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt)

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About This Item

Formula empirica (notazione di Hill):
C40H71N6O13P
Numero CAS:
384833-07-2
Peso molecolare:
875.00
Codice UNSPSC:
12352211
NACRES:
NA.25

Saggio

>99% (TLC)

Forma fisica

liquid

Confezionamento

pkg of 1 × 1 mL (810193C-1mg)

Produttore/marchio commerciale

Avanti Research™ - A Croda Brand 810193C

Concentrazione

1 mg/mL (810193C-1mg)

Condizioni di spedizione

dry ice

Temperatura di conservazione

−20°C

Categorie correlate

Descrizione generale

Phosphoserine (PS) is present in the intracellular membranes and grey matter, and isenriched in the cytosolic leaflet of plasma membrane. NBD PS is a fluorescently labelled lipid with 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the headgroup of PS.

Applicazioni

16:0-06:0 NBD PS or 1-palmitoyl-2-{6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl}-sn-glycero-3-phosphoserine (ammonium salt) may be used in the liposome preparation for in vitro assay of the phosphatidylethanolamine (PE) production by determining the phosphatidylserine decarboxylase 1 (Psd1p) activity.

Azioni biochim/fisiol

Phosphatidylserine (PS) regulates numerous enzymes and structural components maintains the nerve cell membrane and myelin sheath.

Confezionamento

5 mL Amber Glass Screw Cap Vial (810193C-1mg)

Note legali

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organi bersaglio

Central nervous system, Liver,Kidney

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

does not flash

Punto d’infiammabilità (°C)

does not flash

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Yasushi Tamura et al.
The Journal of biological chemistry, 287(52), 43961-43971 (2012-11-06)
Phosphatidylethanolamine (PE) plays important roles for the structure and function of mitochondria and other intracellular organelles. In yeast, the majority of PE is produced from phosphatidylserine (PS) by a mitochondrion-located PS decarboxylase, Psd1p. Because PS is synthesized in the endoplasmic
Jean E Vance et al.
Progress in lipid research, 44(4), 207-234 (2005-06-28)
Phosphatidylserine (PS) is a quantitatively minor membrane phospholipid that is synthesized by prokaryotic and eukaryotic cells. In this review we focus on genes and enzymes that are involved in PS biosynthesis in bacteria, yeast, plants and mammalian cells and discuss
Ouma Onguka et al.
The Journal of biological chemistry, 290(20), 12744-12752 (2015-04-02)
Phosphatidylethanolamine (PE) is a major cellular phospholipid that can be made by four separate pathways, one of which resides in the mitochondrion. The mitochondrial enzyme that generates PE is phosphatidylserine decarboxylase 1 (Psd1p). The pool of PE produced by Psd1p
Michael J Glade et al.
Nutrition (Burbank, Los Angeles County, Calif.), 31(6), 781-786 (2015-05-03)
The aim of this study was to assess the roles and importance of phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain biochemistry, physiology, and function. A scientific literature search was conducted on MEDLINE for relevant articles regarding
Soumi Mukherjee et al.
Chemistry and physics of lipids, 127(1), 91-101 (2004-01-07)
Lipids that are labeled with the NBD (7-nitrobenz-2-oxa-1,3-diazol-4-yl) group are widely used as fluorescent analogues of native lipids in biological and model membranes to monitor a variety of processes. NBD-labeled lipids have previously been used to monitor the organization and
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