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P14815

Sigma-Aldrich

4-Ethoxyaniline

98%

Sinonimo/i:

p-Phenetidine, 4-Ethoxyaniline

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About This Item

Formula condensata:
C2H5OC6H4NH2
Numero CAS:
Peso molecolare:
137.18
Beilstein:
606666
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

Saggio

98%

Indice di rifrazione

n20/D 1.559 (lit.)

P. eboll.

250 °C (lit.)

Punto di fusione

2-5 °C (lit.)

Densità

1.065 g/mL at 25 °C (lit.)

Stringa SMILE

CCOc1ccc(N)cc1

InChI

1S/C8H11NO/c1-2-10-8-5-3-7(9)4-6-8/h3-6H,2,9H2,1H3
IMPPGHMHELILKG-UHFFFAOYSA-N

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Categorie correlate

Pittogrammi

Health hazardExclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Sens. 1

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

251.6 °F - closed cup

Punto d’infiammabilità (°C)

122 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


Certificati d'analisi (COA)

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T Lindqvist et al.
Chemical research in toxicology, 4(4), 489-496 (1991-07-01)
4-Ethoxyaniline (p-phenetidine) is oxidized by peroxidases to form several products, one of which is 4-[(4-ethoxyphenyl)imino]-2,5-cyclohexadien-1-one (1). This compound reacts with N-acetylcysteine (NAC) in methanol-phosphate buffers, generating at least four different products. Four major products, 4-[(4-ethoxyphenyl)amino]phenol (2), 3-(N-acetylcystein-S-yl)-4-[(4-ethoxyphenyl)amino]phenol (3), 2,5-bis(N-acetylcystein-S-yl)-4-[(4-ethoxyphenyl)-amino]phenol (4)
Annabel Kuek et al.
Postgraduate medical journal, 83(978), 251-260 (2007-04-04)
Targeted biologic therapies have revolutionised treatment of immune-mediated inflammatory diseases (IMIDs) due to their efficacy, speed of onset and tolerability. The discovery that clinically unrelated conditions, such as rheumatoid arthritis and Crohn's disease, share similar immune dysregulation has led to
R Larsson et al.
The Journal of pharmacology and experimental therapeutics, 235(2), 475-480 (1985-11-01)
The metabolism of p-phenetidine in microsomes from rabbit kidney and the metabolism of acetaminophen and p-phenetidine in human kidney microsomes to protein binding metabolites were examined. Microsomal preparations from rabbit kidney medulla catalyzed the irreversible arachidonic acid-dependent binding of p-[14C]phenetidine
R Larsson et al.
Chemico-biological interactions, 60(3), 317-330 (1986-12-01)
The interaction of N-(4-ethoxyphenyl)p-benzoquinone imine (NEPBQI), a metabolite formed during peroxidase catalyzed metabolism of p-phenetidine, with GSH and its effects in isolated rat hepatocytes were investigated. When reacted with GSH NEPBQI formed both a mono- and a diglutathione conjugate as
J D Baty et al.
Journal of chromatography, 353, 329-337 (1986-02-26)
Liquid chromatographic methods were developed for the study of the in vitro acetylation of the sulphonamide drug sulphamethazine and a series of aniline derivatives. The sensitivity of the methods have allowed data on the activity of the N-acetyltransferase enzyme(s) in

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