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H3275

Sigma-Aldrich

3-Hydroxy-5-methylisoxazole

≥90%

Sinonimo/i:

Hymexazol

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CHF 119.00
250 MG
CHF 407.00

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50 MG
CHF 119.00
250 MG
CHF 407.00

About This Item

Formula empirica (notazione di Hill):
C4H5NO2
Numero CAS:
Peso molecolare:
99.09
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

CHF 119.00


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Saggio

≥90%

Temperatura di conservazione

2-8°C

Stringa SMILE

CC1=CC(=O)NO1

InChI

1S/C4H5NO2/c1-3-2-4(6)5-7-3/h2H,1H3,(H,5,6)
KGVPNLBXJKTABS-UHFFFAOYSA-N

Descrizione generale

3-Hydroxy-5-methylisoxazole, also known as Hymexazol, is a hydrophilic organic molecule containing both a hydroxy group and a nitrogen atom, which enable it to act as a co-hydrogelator with other components to form self-delivery supramolecular hydrogels. [1]

Applicazioni

3-Hydroxy-5-methylisoxazole can be used as a reactant to synthesize:
  • 3-Oxoisoxazole-2(3H)-carboxamides by reacting with dimethyl-carbamoyl chloride in the presence of potassium t-butoxide[2].
  • Hydroxymethyl-2-propen-1-yl-5-methyl-3(2H)-isoxazolone via ring-opening reaction with vinyl oxirane[3].

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Yongmei Fan et al.
Pesticide biochemistry and physiology, 147, 139-144 (2018-06-24)
Hymexazol is an efficacious and widely used fungicide. However, its environmental toxicological assessment has not been well documented. It had no report of its toxicity to fish embryo. Fish embryo acute toxicity tests are highly predictive of aquatic embryotoxicity outcome.
Qiang Zhang et al.
Journal of agricultural and food chemistry, 62(45), 10962-10969 (2014-10-29)
Bioassay-guided fractionation of the fermentation extract of Xylaria sp. XC-16, an endophyte from Toona sinensis led to the isolation of two new cytochalasans cytochalasin Z27, 1, and cytochalasin Z28, 2, along with three known compounds seco-cytochalasin E, 3, and cytochalasin
Yu-Qi Gao et al.
Journal of agricultural and food chemistry, 68(8), 2418-2425 (2020-02-06)
Two biosynthetically related new metabolites, eucalyptacid A (1) and eucalactam B (2), along with six known compounds (3-8), eugenitol (3), cytosporone C (4), 4-hydroxyphenethyl alcohol (5), 1-(4-hydroxyphenyl)ethane-1,2-diol (6), N-(2-hydroxy-2-phenylethyl)acetamide (7), and phomopene (8), were isolated from the solid rice cultures
Ian Mangion et al.
Organic letters, 11(15), 3258-3260 (2009-07-11)
Hydrazines and hydroxylamines have been found to be excellent nucleophiles for the palladium-catalyzed dynamic asymmetric allylic amination of vinyl epoxide, with good yields and enantioselectivities of up to 97% ee. This method is applicable to acyclic and heterocyclic amines and
Matthew S Brown et al.
Plant disease, 103(7), 1703-1711 (2019-05-21)
During flooding events in nurseries, Phytophthora root rot caused by Phytophthora cinnamomi Rands often causes damage that leads to complete crop loss. In this study, we evaluated the efficacy of fungicides, biofungicides, and host plant defense inducers for preventive and

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