Protons and other cations may inhibit metal uptake and alleviate metal toxicity in aquatic organisms, but less is known about these interactions in soil organisms. The present study investigated the influence of solution chemistry on uptake and toxicity of Ni
Journal of immunology (Baltimore, Md. : 1950), 192(9), 4025-4031 (2014-03-29)
Ni is the most frequent cause of contact allergy induced by metals. However, the underlying mechanism of this induction is unknown. Our previous research demonstrates that activation of dendritic cells (DCs) through p38MAPK/MKK6 is required for Ni-induced allergy in mice.
A general method for the alkenylation of alkyl electrophiles using nearly stoichiometric amounts of the air- and moisture-stable potassium organotrifluoroborates has been developed. Various functional groups were tolerated on both the nucleophilic and electrophilic partner. Reactions of highly substituted E-
Filaggrin is a predominant member of the denaturation-resistant nickel-binding proteome of human epidermis.
Katrine Ross-Hansen et al.
The Journal of investigative dermatology, 134(4), 1164-1166 (2013-10-26)
Nickel is an essential micronutrient due to its involvement in many enzymatic reactions as a cofactor. However, excess of this element is toxic to biological systems. Here, we constructed a cDNA library from Beta maritima and screened it in the
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