909157
Alkyne functionalized gelatin
degree of substitution > 80%
Sinonimo/i:
Alkyne-functionalized gelatin, Clickable gelatin
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Cambia visualizzazione
1 G
CHF 311.00
About This Item
Codice UNSPSC:
43211915
NACRES:
NA.23
Prodotti consigliati
Descrizione
Degree of substitution: >80% by TNBS method
NMR: Conforms to structure
Stato
powder
Colore
white to pale yellow
Temperatura di conservazione
2-8°C
Categorie correlate
Descrizione generale
Due to its biodegradablity and biocompatibility, gelatin is routinely used in hydrogels for biomedical applications such as drug delivery, tissue engineering, and 3D bioprinting. Gelatin-based hydrogels are synthesized by the crosslinking of functionalized gelatins. Depending on the identity of the functional groups, several different processes can be used to synthesize crosslinked gelatin hydrogels, including radical-based (either thermal or photochemical) and click chemistry methods. Alkyne-functionalized gelatin can be used in the synthesis of hydrogel using click chemistry with either azide or thiol substrates.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels.
Yue K, et al.
Biomaterials, 73, 254-271 (2015)
Thiol-yne ′click′/coupling chemistry and recent applications in polymer and materials synthesis and modification.
Lowe AB, et al.
Polymer, 55, 5517-5549 (2014)
Sandeep T Koshy et al.
Advanced healthcare materials, 5(5), 541-547 (2016-01-26)
Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for
Gelatin hydrogels via thiol-ene chemistry.
Russo L, et al.
Monatshefte fur Chemie / Chemical Monthly, 147, 587-592 (2016)
Masato Tamura et al.
Scientific reports, 5, 15060-15060 (2015-10-10)
This paper describes the generation of "click-crosslinkable" and "photodegaradable" gelatin hydrogels from the reaction between dibenzocycloctyl-terminated photoclevable tetra-arm polyethylene glycol and azide-modified gelatin. The hydrogels were formed in 30 min through the click-crosslinking reaction. The micropatterned features in the hydrogels were
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