Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

Visualizza tutta la documentazione

901606

Sigma-Aldrich

tert-Butyl carbazate solution

1.0 M in dichloromethane

Sinonimo/i:

tert-Butoxycarbonyl hydrazide, tert-Butyl hydrazinecarboxylate, Boc-hydrazide

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Formula condensata:
C5H12N2O2
Numero CAS:
870-46-2
Numero MDL:
MFCD00007593
Codice UNSPSC:
12352108

Stato

liquid

Concentrazione

1.0 M in dichloromethane

Indice di rifrazione

n/D 1.427

Densità

1.290 g/mL

Gruppo funzionale

amine
hydrazine

InChI

1S/C5H12N2O2/c1-5(2,3)9-4(8)7-6/h6H2,1-3H3,(H,7,8)
DKACXUFSLUYRFU-UHFFFAOYSA-N

Applicazioni

Employed in a palladium-catalyzed cross-coupling with vinyl halides leading to N-Boc-N-alkenylhydrazines[1].
Reagent used in solid phase peptide synthesis[2] and in α-amino aldehyde optical purity determinations.[3] Condenses with aldehydes to form hydrazones which are intermediates in the synthesis of HIV-1 protease inhibitors.[4]

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

B91005

tert-Butyl carbazate, 98%

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H336,H351

Classi di pericolo

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
MKCH1719

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

José Barluenga et al.
Organic letters, 9(2), 275-278 (2007-01-16)
N-Boc-N-alkenylhydrazines, an almost unknown type of compounds, have been prepared with high to moderate yields via palladium-catalyzed cross-coupling between alkenyl halides and tert-butyl carbazate. The present methodology represents the first general way to access this highly functionalized and unusual type
Zhao Wei et al.
Cell stem cell, 27(5), 798-812 (2020-09-16)
Matrix dynamics influence how individual cells develop into complex multicellular tissues. Here, we develop hydrogels with identical polymer components but different crosslinking capacities to enable the investigation of mechanisms underlying vascular morphogenesis. We show that dynamic (D) hydrogels increase the
Tomáš Etrych et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 58, 1-12 (2014-03-19)
In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly bound via a pH-sensitive hydrazone and partly via
Jeong-A Yang et al.
Acta biomaterialia, 12, 174-182 (2014-10-12)
Liver fibrosis is a chronic liver disease caused by viral infection and/or metabolic, genetic and cholestatic disorders. The inhibition of hepatic stellate cell (HSC) activation and the selective apoptosis of activated HSCs can be a good strategy to treat liver
Joshua O Sestak et al.
The AAPS journal, 16(6), 1185-1193 (2014-09-07)
Presentation of antigen with immune stimulating "signal" has been a cornerstone of vaccine design for decades. Here, the antigen plus immune "signal" of vaccines is modified to produce antigen-specific immunotherapies (antigen-SITs) that can potentially reprogram the immune response toward tolerance

Questions

Reviews

No rating value

Active Filters

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.