803596
BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)
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About This Item
Formula empirica (notazione di Hill):
C16H20N2O7
Peso molecolare:
352.34
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:
NACRES:
NA.22
Prodotti consigliati
Saggio
≥90%
Forma fisica
powder
PM
352.34
Impiego in reazioni chimiche
reagent type: cross-linking reagent
Condizioni di stoccaggio
desiccated
Solubilità
water: soluble
Condizioni di spedizione
ambient
Temperatura di conservazione
2-8°C
Stringa SMILE
O=C(C=CC1=O)N1CCOCCOCCOCCN2C(C=CC2=O)=O
InChI
1S/C16H20N2O7/c19-13-1-2-14(20)17(13)5-7-23-9-11-25-12-10-24-8-6-18-15(21)3-4-16(18)22/h1-4H,5-12H2
OYRSKXCXEFLTEY-UHFFFAOYSA-N
Descrizione generale
BM(PEG)2 and BM(PEG)3 are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e. oligomerization) or protein interactions. Because BM(PEG)2 and BM(PEG)3 have the same reactivity but differ in length, the relative success of these and similar reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.
Caratteristiche e vantaggi
- Reactive groups: maleimide (both ends)
- Reactive towards: sulfhydryl groups
- Long, pegylated, sulfhydryl-to-sulfhydryl crosslinkers, composed of maleimide groups and 3-unit polyethylene glycol spacer arm
- PEG spacers provide unique advantages, including enhanced solubility, increased stability, reduced tendency toward aggregation and reduced immunogenicity
- Pure compounds with defined structure and molecular weight, ensuring reproducible protein-modification effects
- Ideal for small molecule or peptide conjugations
Avvertenza
This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Organi bersaglio
Respiratory system
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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