Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

Visualizza tutta la documentazione

764779

Sigma-Aldrich

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)

PEG average Mn 2,000, PDLLA average Mn 2,000

Sinonimo/i:

PEG-PDLLA

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali

Scegli un formato

1 G
CHF 276.00

CHF 276.00

Check Cart for Availability
Richiedi un ordine bulk
Tutte le immagini(1)

Scegli un formato

Cambia visualizzazione
1 G
CHF 276.00

About This Item

Codice UNSPSC:
12162002
NACRES:
NA.23

CHF 276.00

Check Cart for Availability
Richiedi un ordine bulk

Descrizione

n=45, m=28 (typical)
typical PEG PDI<1.1; overall PDI<1.4 (THF, PEO)

Stato

pellets

PM

PDLLA average Mn 2,000
PEG average Mn 2,000
average Mn 4,000 (total)

Tempo di degradazione

2-4 weeks

Temp. transizione

Tg 11 °C (PEG block)
Tm 244-248 °C
Tg 88 °C (PDLLA block)

Ind. polidispersione

≤1.4

Temperatura di conservazione

2-8°C

Categorie correlate

Descrizione generale

Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as carriers for hydrophobic drugs like paclitaxel. PEG is the hydrophilic part and PDLLA is the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded.[1]

Applicazioni

Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs. [2]
water-solubilization of drugs

Caratteristiche e vantaggi

  • Good biocompatibility, low immunogenicity and good degradability.
  • Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application. [1]

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
MKCS6562
MKCM3361
MKCJ7857
MKCG4708
MKCD4773

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

I clienti hanno visto anche

Slide 1 of 1

1 of 1

Methoxy poly(ethylene glycol)-b-poly(D,L-lactide) 2k-5k

Sigma-Aldrich

900657

Methoxy poly(ethylene glycol)-b-poly(D,L-lactide)

Hongtao Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 105(18), 6596-6601 (2008-05-01)
It is generally assumed that polymeric micelles, upon administration into the blood stream, carry drug molecules until they are taken up into cells followed by intracellular release. The current work revisits this conventional wisdom. The study using dual-labeled micelles containing
Arunvel Kailasan et al.
Acta biomaterialia, 6(3), 1131-1139 (2009-09-01)
This work describes the synthesis and characterization of novel thermoresponsive highly branched polyamidoamine-polyethylene glycol-poly(D,L-lactide) (PAMAM-PEG-PDLLA) core-shell nanoparticles. A series of dendritic PEG-PDLLA nanoparticles were synthesized through conjugation of PEG of various chain lengths (1500, 6000 and 12,000 g mol(-1)) to

Articoli

Electrospun Nanofibers for Drug Delivery Systems

Local delivery of bioactive molecules using an implantable device can decrease the amount of drug dose required as well as non-target site toxicities compared to oral or systemic drug administration.

Biodegradable Polyester Nanoparticle Formation

AliAliphatic polyesters, including polylactide and polyglycolide, are biodegradable polymers widely used in medical applications.

Polymersomes for Drug Delivery

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

Questions

Reviews

No rating value

Active Filters

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.