746118

Sodium difluoroheptylazidosulfinate

95%

• Sinonimo/i: Baran DAAS-Na Reagent, Sodium 1,1-difluoro-7-azido-heptylsulfinate, Sodium 7-azido-1,1-difluoroheptanesulfinate
• Formula empirica (notazione di Hill): C₇H₁₂F₂N₃NaO₂S
• Numero CAS: 1450912-63-6
• Peso molecolare: 263.24
• Codice UNSPSC: 12352125
• ID PubChem: 329765744
• NACRES: NA.22

Proprietà

• Saggio: 95%
• Forma fisica: solid
• Impiego in reazioni chimiche: reaction type: C-C Bond Formation; reagent type: catalyst; reaction type: C-H Activation; reagent type: linker
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: [Na+].[O-]S(=O)C(F)(F)CCCCCCN=[N+]=[N-]
• InChI: 1S/C7H13F2N3O2S.Na/c8-7(9,15(13)14)5-3-1-2-4-6-11-12-10;/h1-6H2,(H,13,14);/q;+1/p-1; FFNHIEJQAMGBCZ-UHFFFAOYSA-M

Descrizione

Applicazioni

Within heteroarene platforms, DAAS-Na allows for the direct introduction of a difluoroalkyl chain carrying an azide group, which is designed for the purpose of bioconjugation. Through a Huisgen cycloaddition (a "click" reaction), the azide moiety can then be reacted with a terminal alkyne that is bound to a functional molecule such as biomacromolecules. This effectively allows for a covalent linkage between a heteroarene and any target molecule, for example, between a heteroarene-containing drug and an antibody. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.

Learn More at the Professor and Product Portal of Professor Phil S. Baran.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319,H335
• Consigli di prudenza: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable