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Documenti fondamentali

60034

Sigma-Aldrich

4-Aminophenol

≥99% (HPLC)

Sinonimo/i:

4-Hydroxyaniline

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About This Item

Formula condensata:
H2NC6H4OH
Numero CAS:
Peso molecolare:
109.13
Beilstein:
385836
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:

Saggio

≥99% (HPLC)

Forma fisica

powder

Punto di fusione

185-189 °C (lit.)
186-188 °C

Solubilità

water: slightly soluble

Stringa SMILE

Nc1ccc(O)cc1

InChI

1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2
PLIKAWJENQZMHA-UHFFFAOYSA-N

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Descrizione generale

4-Aminophenol is an organic building block. Its voltammetric estimation in water samples by employing single-wall carbon nanotubes (SWNT)-Nafion film coated glassy carbon electrode has been reported. It is present as the main contaminant in the pharmaceutical formulation of paracetamol. Its quantification in multicomponent dosage preparations of paracetamol by HPLC coupled with amperometric detection has been described.

Applicazioni

4-Aminophenol may be used in the synthesis of 2,2-bis(4-aminophenoxy) benzonitrile [4-APBN], a monomer required for the preparation of series of polyamides and poly(amide-imide)s. It may be used as derivatization reagent during paper spray ionization mass spectrometric estimation of aldehydes.

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2

Organi bersaglio

Kidney

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Synthesis and characterization of polyamides and poly (amide-imide) s derived from 2, 2-bis (4-aminophenoxy) benzonitrile.
Saxena A, et al.
European Polymer Journal, 39(2), 401-405 (2003)
Pravin B Patil et al.
Ultrasonics sonochemistry, 70, 105306-105306 (2020-08-17)
The present study reports significant improvements in the removal of ammoniacal nitrogen from wastewater which is an important problem for many industries such as dyes and pigment, distilleries and fisheries. Pilot plant studies (capacity, 1 m3/h) on synthetic wastewater using 4-amino
E Wyszecka-Kaszuba et al.
Journal of pharmaceutical and biomedical analysis, 32(4-5), 1081-1086 (2003-08-06)
A method for the determination of 4-aminophenol, the main impurity of paracetamol, by high-performance liquid chromatographic (HPLC) method with amperometric detection has been developed. The analysis was performed in an isocratic mode on a reversed phase Luna column 5 microm
Wensheng Huang et al.
Talanta, 61(3), 411-416 (2008-10-31)
A single-wall carbon nanotubes (SWNT)-Nafion film coated glassy carbon electrode (GCE) was described for the determination of 4-aminophenol. In pH 3.0 sodium citrate-HCl buffer, the oxidation peak current of 4-aminophenol increases greatly at the SWNT-Nafion film coated GCE in contrast
Y Xu et al.
Clinical chemistry, 36(11), 1941-1944 (1990-11-01)
A sandwich-type heterogeneous enzyme immunoassay with flow-injection analysis for alpha-fetoprotein (AFP) in human serum has been developed. 4-Aminophenol, the product of enzymatic reaction, is detected amperometrically. The interassay CV for this electrochemical enzyme immunoassay was less than 8.2%, with a

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