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248010

Sigma-Aldrich

3,5-Dichloro-2,4,6-trifluoropyridine

98%

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About This Item

Formula empirica (notazione di Hill):
C5Cl2F3N
Numero CAS:
Peso molecolare:
201.96
Numero CE:
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:

Saggio

98%

Stato

liquid

Indice di rifrazione

n20/D 1.478 (lit.)

P. ebollizione

159-160 °C (lit.)

Densità

1.622 g/mL at 25 °C (lit.)

Stringa SMILE

Fc1nc(F)c(Cl)c(F)c1Cl

InChI

1S/C5Cl2F3N/c6-1-3(8)2(7)5(10)11-4(1)9
PKSORSNCSXBXOT-UHFFFAOYSA-N

Descrizione generale

The solid phase mid FTIR and FT-Raman spectra of 3,5-dichloro-2,4,6-trifluoropyridine has been recorded in the region of 3500-100 cm-1. 3,5-Dichloro-2,4,6-trifluoropyridine reacts with Ni(1,5,-cyclooctadiene)2 in the presence of triethylphosphine (PEt3) to yield trans-Ni(PEt3)2(C5ClF3N)Cl.

Applicazioni

3,5-Dichloro-2,4,6-trifluoropyridine has been used in the preparation of Avid AL, an affinity gel designed for the purification of immunoglobulin G.

Pittogrammi

Skull and crossbones

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 1 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

235.4 °F - closed cup

Punto d’infiammabilità (°C)

113 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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V C Lees et al.
Burns : journal of the International Society for Burn Injuries, 18(5), 423-425 (1992-10-01)
An example is reported of a burn caused by cutaneous exposure to 3,5-dichloro 2,4,6-trifluoropyridine (DCTFP) involving 25 per cent of the body surface. A striking feature was the development of the appearance of the burn over the first 72h postinjury.
T T Ngo
Journal of chromatography. B, Biomedical applications, 662(2), 351-356 (1994-12-09)
A derivative of aza-arenophilic gel having a dichlorosubstituent and an hydroxy ion as a capping nucleophile has been prepared. The properties of this gel in relation to IgG purification have been investigated in details. In the presence of high salt
V Krishnakumar et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 61(1-2), 253-260 (2004-11-24)
The solid phase mid FTIR and FT-Raman spectra of 3,5-dibromopyridine (3,5-DBP) and 3,5-dichloro-2,4,6-trifluoropyridine (3,5-DCTFP) have been recorded in the regions 4000-400 cm(-1) and 3500-100 cm(-1), respectively. The spectra were interpreted with the help of normal coordinate analysis (NCA) following full
Xiaoying Hui et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(7), 2496-2502 (2012-04-17)
This in vitro study determined the decontamination potential of soap and water, D-TAM skin cleanser, corn oil and the O'Dell reactive skin decontamination system to remove 3,5-dichloro-2,4,6-trifluoropyridine (DCTFP) from human skin after short exposure periods (10 and 30 min). The
Rapid intermolecular carbon-fluorine bond activation of pentafluoropyridine at nickel (0): Comparative reactivity of fluorinated arene and fluorinated pyridine derivatives.
Cronin L, et al.
Organometallics, 16(22), 4920-4928 (1997)

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