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202495

Sigma-Aldrich

Poly(ethylene glycol) methyl ether

average MN 750, methoxy, hydroxyl

Sinonimo/i:

Polyethylene glycol monomethyl ether

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About This Item

Formula condensata:
CH3(OCH2CH2)nOH
Numero CAS:
9004-74-4
Numero MDL:
MFCD00084416
Codice UNSPSC:
12162002
ID PubChem:
24852093
NACRES:
NA.23

product name

Poly(ethylene glycol) methyl ether, average Mn 750

Densità del vapore

>1 (vs air)

Tensione di vapore

0.05 mmHg ( 20 °C)

Forma fisica

paste
solid

PM

average Mn 750

Indice di rifrazione

n20/D 1.459

Viscosità

10.5 cSt(210 °F)(lit.)

Temp. transizione

Tm 30 °C

Densità

1.094 g/mL at 25 °C

Estremità Ω

hydroxyl

Estremità α

methoxy

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3
XNWFRZJHXBZDAG-UHFFFAOYSA-N

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Applicazioni

Poly(ethylene glycol) methyl ether can be used:
  • As a chain transfer agent to synthesize amphiphilic block copolymers by metal-free ring-opening oligomerization.
  • As a precursor to prepare retinoic acid-polyethylene glycol nanoassembly as an efficient drug delivery system.
  • To prepare diblock copolymer with polylactic acid, which can be applied in the field of tissue engineering and drug delivery.

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

359.6 °F - closed cup

Punto d’infiammabilità (°C)

182 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves

Certificati d'analisi (COA)

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Poly(ethylene glycol) methyl ether tosylate average Mn 900

Sigma-Aldrich

729116

Poly(ethylene glycol) methyl ether tosylate

Methoxypolyethylene glycol maleimide 750

Sigma-Aldrich

712558

Methoxypolyethylene glycol maleimide

Lei Liu et al.
International journal of pharmaceutics, 443(1-2), 175-182 (2013-01-05)
This work aims to develop curcumin (Cur) loaded biodegradable self-assembled polymeric micelles (Cur-M) to overcome poor water solubility of Cur and to meet the requirement of intravenous administration. Cur-M were prepared by solid dispersion method, which was simple and easy
Yi Wei et al.
Langmuir : the ACS journal of surfaces and colloids, 28(39), 13984-13992 (2012-09-04)
The microcosmic mechanisms of protein (recombinant human growth hormone, rhGH) incomplete release and stability from amphiphilic poly(monomethoxypolyethylene glycol-co-D,L-lactide) (mPEG-PLA, PELA) microspheres were investigated. PELA with different hydrophilicities (PELA-1, PELA-2, and PELA-3) based on various ratios of mPEG to PLA were
Junhwa Shin et al.
Molecular pharmaceutics, 9(11), 3266-3276 (2012-10-04)
A family of 3-methoxypoly(ethylene glycol)-vinyl ether-1,2-dioleylglycerol (mPEG-VE-DOG) lipopolymer conjugates, designed on the basis of DFT calculations to possess a wide range of proton affinities, was synthesized and tested for their hydrolysis kinetics in neutral and acidic buffers. Extruded ∼100 nm
Yunki Lee et al.
Colloids and surfaces. B, Biointerfaces, 102, 585-589 (2012-10-30)
The control of biological interactions that occur at material-cell/blood interfaces is of great importance to help maximize in vitro and in vivo performance of biomedical devices. PEGylation has been extensively used as an effective surface modification tool that can alter
Yiyi Yu et al.
Journal of pharmaceutical sciences, 102(3), 1054-1062 (2013-01-03)
To promote the application of methoxy poly(ethylene glycol)-cholesterol (mPEG-Chol), mPEG-Chol was used to prepare core-shell micelles encapsulating poorly water-soluble docetaxel (DTX-PM) by modified cosolvent evaporation method. Approaches to enhance DTX entrapment efficiency (EE) and minimize particle size were investigated in
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